In the first comprehensive examination of strenuous physical activity and the risk of developing Parkinson’s disease, researchers from the Harvard School of Public Health (HSPH) have found that men who exercised regularly and vigorously early in their adult life had a lower risk for developing Parkinson’s disease compared to men who did not. The findings appear in the February 22, 2005 issue of the journal Neurology. Parkinson’s disease is a progressive nervous disease occurring generally after age 50. It destroys brain cells that produce dopamine and is characterized by muscular tremor, slowing of movement, rigidity and postural instability.
Men who were the most physically active at the start of the study cut their risk of developing Parkinson’s disease by 50 percent compared to men study participants who were the least physically active. The authors also found that men who reported regularly having engaged in strenuous physical activity in early adult life cut the risk for Parkinson’s by 60 percent compared to those who did not.
Among women in the study, strenuous activity in the early adult years was also linked to a lower risk of Parkinson’s, but this relationship was not statistically significant, and there was no clear relationship between physical activity later in life and Parkinson’s risk.
Kevin C. Myron | EurekAlert!
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Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.
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At TU Wien, an alternative for resource intensive formwork for the construction of concrete domes was developed. It is now used in a test dome for the Austrian Federal Railways Infrastructure (ÖBB Infrastruktur).
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Many pathogens use certain sugar compounds from their host to help conceal themselves against the immune system. Scientists at the University of Bonn have now, in cooperation with researchers at the University of York in the United Kingdom, analyzed the dynamics of a bacterial molecule that is involved in this process. They demonstrate that the protein grabs onto the sugar molecule with a Pac Man-like chewing motion and holds it until it can be used. Their results could help design therapeutics that could make the protein poorer at grabbing and holding and hence compromise the pathogen in the host. The study has now been published in “Biophysical Journal”.
The cells of the mouth, nose and intestinal mucosa produce large quantities of a chemical called sialic acid. Many bacteria possess a special transport system...
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