Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Over Prescribing Causing High Rates Of Antibiotic Resistance in South And East Europe

11.02.2005


Resistance to antibiotics is more common in southern and eastern Europe than in northern Europe because the regions have high rates of antibiotic use, suggests a study published in this week’s issue of THE LANCET.



Herman Goossens (University of Antwerp, Belgium) and colleagues compared antibiotic use with antibiotic resistance rates in 26 European countries from the beginning of 1997 to the end of 2002. To control for the different population sizes the investigators expressed data in defined daily dose per 1000 inhabitants daily (DID).

The study found that the prescription of antibiotics in primary care in Europe vary greatly. The highest rate was in France (32.2 DID) and the lowest was in the Netherlands (10.0 DID). Across Europe antibiotic use was lower in northern, moderate in eastern and higher in southern regions. Seasonal fluctuations were high in southern and eastern European countries, whereas in northern European countries the increase in antibiotic use during the winter was less than 25%. In most countries the researchers found a growing use of the newer antibiotics (active against a broad spectrum of micro-organisms) and a decline in use of the older antibiotics (active against a narrow spectrum of micro-organisms).


The authors believe the data will be useful for assessing public health strategies that aim to reduce inappropriate antibiotic use and resistance levels. In the article they write that the differences in antibiotic use between countries might be explained by variations in incidence of community infections, culture and education, differences in drug relations and in the structure of the national pharmaceutical market.

Professor Goossens concludes: “Population-based studies are needed to determine the motivation and incentives that lead individuals to use or not to use antibiotics. The ethics of promoting antibiotics in clinical situations in which they are unnecessary should be given serious consideration. In view of the emergence of bacterial resistance and the decline in the rate of development of novel antibiotics, effective professional and public strategies to encourage appropriate prescribing of antibiotics should be studied and implemented. If not, we will lose the miracle drugs of the 20th century.”

In an accompanying commentary John Turnidge (Women’s and Children’s Hospital, North Adelaide, Australia) and Keryn Christiansen (Royal Perth Hospital, Perth, Australia) state that the method used by Goossens and colleagues to correlate antimicrobial use with resistance has been effective but crude.

Professor Turnidge comments: “If we develop more sophisticated systems to measure antimicrobial use that incorporate the many influences, such as the proportion of individuals exposed, the proportion of children in the population, population densities, the effects of different drug classes, and the differences between bacterial species, it will help us to design and measure the success of intervention strategies.”

Udani Samarasekera | alfa
Further information:
http://www.thelancet.com

More articles from Health and Medicine:

nachricht Research offers clues for improved influenza vaccine design
09.04.2018 | NIH/National Institute of Allergy and Infectious Diseases

nachricht Injecting gene cocktail into mouse pancreas leads to humanlike tumors
06.04.2018 | University of Texas Health Science Center at San Antonio

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Writing and deleting magnets with lasers

Study published in the journal ACS Applied Materials & Interfaces is the outcome of an international effort that included teams from Dresden and Berlin in Germany, and the US.

Scientists at the Helmholtz-Zentrum Dresden-Rossendorf (HZDR) together with colleagues from the Helmholtz-Zentrum Berlin (HZB) and the University of Virginia...

Im Focus: Gamma-ray flashes from plasma filaments

Novel highly efficient and brilliant gamma-ray source: Based on model calculations, physicists of the Max PIanck Institute for Nuclear Physics in Heidelberg propose a novel method for an efficient high-brilliance gamma-ray source. A giant collimated gamma-ray pulse is generated from the interaction of a dense ultra-relativistic electron beam with a thin solid conductor. Energetic gamma-rays are copiously produced as the electron beam splits into filaments while propagating across the conductor. The resulting gamma-ray energy and flux enable novel experiments in nuclear and fundamental physics.

The typical wavelength of light interacting with an object of the microcosm scales with the size of this object. For atoms, this ranges from visible light to...

Im Focus: Basel researchers succeed in cultivating cartilage from stem cells

Stable joint cartilage can be produced from adult stem cells originating from bone marrow. This is made possible by inducing specific molecular processes occurring during embryonic cartilage formation, as researchers from the University and University Hospital of Basel report in the scientific journal PNAS.

Certain mesenchymal stem/stromal cells from the bone marrow of adults are considered extremely promising for skeletal tissue regeneration. These adult stem...

Im Focus: Like a wedge in a hinge

Researchers lay groundwork to tailor drugs for new targets in cancer therapy

In the fight against cancer, scientists are developing new drugs to hit tumor cells at so far unused weak points. Such a “sore spot” is the protein complex...

Im Focus: The Future of Ultrafast Solid-State Physics

In an article that appears in the journal “Review of Modern Physics”, researchers at the Laboratory for Attosecond Physics (LAP) assess the current state of the field of ultrafast physics and consider its implications for future technologies.

Physicists can now control light in both time and space with hitherto unimagined precision. This is particularly true for the ability to generate ultrashort...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

Unique scope of UV LED technologies and applications presented in Berlin: ICULTA-2018

12.04.2018 | Event News

IWOLIA: A conference bringing together German Industrie 4.0 and French Industrie du Futur

09.04.2018 | Event News

 
Latest News

Diamond-like carbon is formed differently to what was believed -- machine learning enables development of new model

19.04.2018 | Materials Sciences

Electromagnetic wizardry: Wireless power transfer enhanced by backward signal

19.04.2018 | Physics and Astronomy

Ultrafast electron oscillation and dephasing monitored by attosecond light source

19.04.2018 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>