Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Combating blindness is vision of UT, ORNL project

10.02.2005


Millions of people at risk of becoming blind could one day be helped by an Oak Ridge National Laboratory technology originally intended to understand semiconductor defects.



The project takes advantage of the Department of Energy lab’s proprietary content-based image retrieval technology, which is a method for sorting and finding visually similar images in large databases. Manufacturers of semiconductors have found this technology highly effective for rapidly scanning hundreds of thousands of tiny semiconductors to learn quickly about problems with manufacturing processes.

"We’re adapting a proven technology and combining it with new image gathering and analysis tools to help create a database to assist in the diagnosis and treatment of blinding eye diseases such as diabetic retinopathy, glaucoma and age-related macular degeneration," said project co-leader Ken Tobin of ORNL’s Engineering Science & Technology Division.


Diabetic retinopathy alone will affect 239 million people worldwide by 2010, according to Tobin, who noted that this number will have doubled since 1994. Partnering with ORNL is Edward Chaum, an ophthalmologist and Plough Foundation professor of retinal diseases at the University of Tennessee Health Science Center in Memphis.

Researchers plan to use digital retinal photography and optical coherence tomography -- a technique for examining living tissue non-invasively -- to image and quantify specific disease-based changes in the retina. They will develop an extensive image database of known retinal disease states for clinical validation studies.

Institutional Review Board approval was secured to enable Tobin and ORNL colleagues Tom Karnowski and Priya Govindasamy to assemble a database of thousands of fluorescein angiography and optical coherence tomography images representing hundreds of diagnosed human patients and retinal diseases. "The dataset provided by Dr. Chaum documents the visual attributes of fluorescein angiography and optical coherence tomography imagery that are used to diagnose a wide range of pathologies," Tobin said. "This is a necessary step to support developing our statistical feature descriptions for image indexing, retrieval and diagnosis."

Tobin and Chaum expect this project to provide benefits not only for diagnosing and treating blinding diseases in broad-based population screening programs, but also for novel biomedical imaging and telemedicine. "With 180 million people worldwide either blind or at risk of becoming blind, this research has a chance to make a profound effect on people’s lives," Chaum said. "By developing a computer diagnosis system to improve early detection of eye disease by non-experts and through telemedicine, we can potentially treat or prevent up to 80 percent of blindness."

Funding for the project, which began in June 2004, is provided by ORNL’s Laboratory Directed Research and Development program. ORNL, which is managed by UT-Battelle, employs 1,500 scientists and engineers and is the Department of Energy’s largest multipurpose science and energy laboratory.

Ron Walli | EurekAlert!
Further information:
http://www.ornl.gov

More articles from Health and Medicine:

nachricht Observing the cell's protein factories during self-assembly
15.06.2018 | Charité - Universitätsmedizin Berlin

nachricht Scientists unravel molecular mechanisms of Parkinson's disease
13.06.2018 | The Francis Crick Institute

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: AchemAsia 2019 will take place in Shanghai

Moving into its fourth decade, AchemAsia is setting out for new horizons: The International Expo and Innovation Forum for Sustainable Chemical Production will take place from 21-23 May 2019 in Shanghai, China. With an updated event profile, the eleventh edition focusses on topics that are especially relevant for the Chinese process industry, putting a strong emphasis on sustainability and innovation.

Founded in 1989 as a spin-off of ACHEMA to cater to the needs of China’s then developing industry, AchemAsia has since grown into a platform where the latest...

Im Focus: First real-time test of Li-Fi utilization for the industrial Internet of Things

The BMBF-funded OWICELLS project was successfully completed with a final presentation at the BMW plant in Munich. The presentation demonstrated a Li-Fi communication with a mobile robot, while the robot carried out usual production processes (welding, moving and testing parts) in a 5x5m² production cell. The robust, optical wireless transmission is based on spatial diversity; in other words, data is sent and received simultaneously by several LEDs and several photodiodes. The system can transmit data at more than 100 Mbit/s and five milliseconds latency.

Modern production technologies in the automobile industry must become more flexible in order to fulfil individual customer requirements.

Im Focus: Sharp images with flexible fibers

An international team of scientists has discovered a new way to transfer image information through multimodal fibers with almost no distortion - even if the fiber is bent. The results of the study, to which scientist from the Leibniz-Institute of Photonic Technology Jena (Leibniz IPHT) contributed, were published on 6thJune in the highly-cited journal Physical Review Letters.

Endoscopes allow doctors to see into a patient’s body like through a keyhole. Typically, the images are transmitted via a bundle of several hundreds of optical...

Im Focus: Photoexcited graphene puzzle solved

A boost for graphene-based light detectors

Light detection and control lies at the heart of many modern device applications, such as smartphone cameras. Using graphene as a light-sensitive material for...

Im Focus: Water is not the same as water

Water molecules exist in two different forms with almost identical physical properties. For the first time, researchers have succeeded in separating the two forms to show that they can exhibit different chemical reactivities. These results were reported by researchers from the University of Basel and their colleagues in Hamburg in the scientific journal Nature Communications.

From a chemical perspective, water is a molecule in which a single oxygen atom is linked to two hydrogen atoms. It is less well known that water exists in two...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Munich conference on asteroid detection, tracking and defense

13.06.2018 | Event News

2nd International Baltic Earth Conference in Denmark: “The Baltic Sea region in Transition”

08.06.2018 | Event News

ISEKI_Food 2018: Conference with Holistic View of Food Production

05.06.2018 | Event News

 
Latest News

Novel method for investigating pore geometry in rocks

18.06.2018 | Earth Sciences

Diamond watch components

18.06.2018 | Process Engineering

New type of photosynthesis discovered

18.06.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>