New technology can screen for multiple agents simultaneously; has potential applications for clinical medicine, biodefense, vaccine development, blood product industry
Researchers at Columbia Universitys Mailman School of Public Health and the Columbia Genome Center have designed and developed a sensitive new diagnostic technology platform, called "Mass Tag PCR," that can simultaneously screen for multiple infectious agents. The new technology is addressed in a paper published in the February issue of the Centers for Disease Control and Preventions (CDC) Emerging Infectious Diseases. This new platform is demonstrated in an assay that detects and discriminates 22 pathogens including viruses and bacteria that can present as clinically similar pulmonary disease.
This new technology platform addresses important challenges for infectious disease identification-sensitivity and breadth. Mass Tag PCR provides the ability to be precise in identification, as well as the ability to apply current diagnostics to more than one pathogen at a time, thereby reducing the time needed for differential diagnosis.
Stephanie Berger | EurekAlert!
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