Mayo Clinic researchers have found that rheumatoid arthritis patients have twice the risk of heart failure, or a weakening of the heart’s ability to pump blood, as those without rheumatoid arthritis, according to a new study to be published in the February edition of the journal Arthritis & Rheumatism. About one-third of the rheumatoid arthritis patients studied developed heart failure over 30 years of the disease.
"We decided to undertake this study because we knew that patients with rheumatoid arthritis die earlier than the general population, and mostly from heart disease," says Paulo Nicola, M.D., Mayo Clinic research fellow in the Department of Health Sciences Research and study author. "We thought heart failure could be a reason for early mortality in these patients. However, we were not expecting that the incidence of heart failure would be so high."
The study found that patients with rheumatoid arthritis are at an increased risk for heart failure soon after the onset of arthritis and that this elevated risk follows them throughout the course of the arthritis, a chronic disease. The researchers also found that the factors putting them at this increased risk for heart failure seem to be unrelated to heart attacks and to the traditional cardiovascular risk factors: diabetes; alcohol abuse; and elevated cholesterol, blood pressure and body mass index. The source of the increased risk remains a mystery, however.
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The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.
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