Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

How the brain creates false memories

02.02.2005


Lawyers are often suspicious of so-called "eye-witness accounts" and rightly so. Hundreds of scientific studies in the past few decades have shown that the memories of people who observe complex events are notoriously susceptible to alteration if they receive misleading information about the event after it has taken place. In this month’s issue of the journal Learning & Memory, scientists from Johns Hopkins University report new insights into how such "false memories" are formed. This is the first study to use neuroimaging to investigate how the brain encodes misinformation during the creation of a false memory.



Using advanced, non-invasive imaging techniques, Yoko Akado and Craig Stark compared the areas of the brain that were active when a subject was encoding a complex event and afterwards, during exposure to misleading information. For example, subjects were asked to watch a vignette comprised of 50 photographic slides showing a man stealing a woman’s wallet, then hiding behind a door. A little later, the subjects were shown what they thought was the same sequence of slides but unbeknownst to them the second set of slides contained a misleading item and differed in small ways from the original--the man hid behind a tree, for example, not a door.

Two days later, the subjects took a memory test, which asked them to recall details such as where the man hid, and which presentation--the first, second, or both--contained that information. Memory for a misinformation item was scored as a false memory only if the subject attributed the item to either the original presentation or to both the original and second slide presentations.


Stark and Akado found clear evidence that the subjects’ brain activity predicted if their memories of the theft would be accurate or false. Consistent with findings from numerous previous studies that have reported that areas such as the hippocampus are highly active during memory formation, Okado and Stark found activity in the left hippocampus tail as well as perirhinal cortex was correlated with successful encoding of an item in memory, even when the memory that was formed was for a false item. But in subjects who had formed false memories, it was noticeable that activity in other brain areas such as the prefrontal cortex was weak during exposure to the second sequence of slides compared to during the original viewing.

Okada and Stark suggest that activity in the prefrontal cortex is correlated to encoding the source, or context, of the memory. Thus, weak prefrontal cortex activity during the misinformation phase indicaates that the details of the second experience were poorly placed in a learning context, and as a result more easily embedded in the context of the first event, creating false memories.

Susan J. Cushman | EurekAlert!
Further information:
http://www.uth.tmc.edu

More articles from Health and Medicine:

nachricht GLUT5 fluorescent probe fingerprints cancer cells
20.04.2018 | Michigan Technological University

nachricht Scientists re-create brain neurons to study obesity and personalize treatment
20.04.2018 | Cedars-Sinai Medical Center

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Spider silk key to new bone-fixing composite

University of Connecticut researchers have created a biodegradable composite made of silk fibers that can be used to repair broken load-bearing bones without the complications sometimes presented by other materials.

Repairing major load-bearing bones such as those in the leg can be a long and uncomfortable process.

Im Focus: Writing and deleting magnets with lasers

Study published in the journal ACS Applied Materials & Interfaces is the outcome of an international effort that included teams from Dresden and Berlin in Germany, and the US.

Scientists at the Helmholtz-Zentrum Dresden-Rossendorf (HZDR) together with colleagues from the Helmholtz-Zentrum Berlin (HZB) and the University of Virginia...

Im Focus: Gamma-ray flashes from plasma filaments

Novel highly efficient and brilliant gamma-ray source: Based on model calculations, physicists of the Max PIanck Institute for Nuclear Physics in Heidelberg propose a novel method for an efficient high-brilliance gamma-ray source. A giant collimated gamma-ray pulse is generated from the interaction of a dense ultra-relativistic electron beam with a thin solid conductor. Energetic gamma-rays are copiously produced as the electron beam splits into filaments while propagating across the conductor. The resulting gamma-ray energy and flux enable novel experiments in nuclear and fundamental physics.

The typical wavelength of light interacting with an object of the microcosm scales with the size of this object. For atoms, this ranges from visible light to...

Im Focus: Basel researchers succeed in cultivating cartilage from stem cells

Stable joint cartilage can be produced from adult stem cells originating from bone marrow. This is made possible by inducing specific molecular processes occurring during embryonic cartilage formation, as researchers from the University and University Hospital of Basel report in the scientific journal PNAS.

Certain mesenchymal stem/stromal cells from the bone marrow of adults are considered extremely promising for skeletal tissue regeneration. These adult stem...

Im Focus: Like a wedge in a hinge

Researchers lay groundwork to tailor drugs for new targets in cancer therapy

In the fight against cancer, scientists are developing new drugs to hit tumor cells at so far unused weak points. Such a “sore spot” is the protein complex...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

Unique scope of UV LED technologies and applications presented in Berlin: ICULTA-2018

12.04.2018 | Event News

IWOLIA: A conference bringing together German Industrie 4.0 and French Industrie du Futur

09.04.2018 | Event News

 
Latest News

Magnetic nano-imaging on a table top

20.04.2018 | Physics and Astronomy

Start of work for the world's largest electric truck

20.04.2018 | Interdisciplinary Research

Atoms may hum a tune from grand cosmic symphony

20.04.2018 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>