Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Simpler ’alphabet’ guidelines for treating acute coronary syndrome reduce risk

19.01.2005


A simplified approach to the management of patients with an acute coronary syndrome (chest pain at rest or with mild exertion) can help ensure that precise risk-reducing strategies are followed to the letter by doctors and other caregivers of patients with this medical condition, according to a study by Johns Hopkins researchers.

"Many doctors think existing guidelines are lengthy and complex and therefore difficult to implement in the clinic and at home by patients," says Roger S. Blumenthal, M.D., associate professor of medicine, director of the Ciccarone Preventive Cardiology Center at Johns Hopkins, and senior investigator of the study, published in the Jan. 19 issue of the Journal of the American Medical Association.
The new guidelines are based on those developed by the American College of Cardiology (ACG),the American Heart Association (AHA) and the results of recent clinical trials, and include risk-factor reduction, lifestyle changes and drugs.


To develop the guidelines, the researchers reviewed all of the relevant peer-reviewed medical publications from 1990 to 2004 in order to assess the most effective and safest practices. They conclude that once patients most likely to benefit from either an early invasive or early conservative strategy are identified, a comprehensive management plan following a simple "ABCDE" approach can be applied.

The "alphabet" approach includes "A" for antiplatelet therapy, anticoagulation, angiotensin converting enzyme inhibition, and angiotensin receptor blockade; "B" for beta-blockade and blood pressure control; "C" for cholesterol treatment and cigarette smoking cessation; "D" for diabetes management and diet; and "E" for exercise.

For the study, the researchers focused on one type of coronary artery disease, called non-ct-segment elevation acute coronary syndrome. According to the AHA, acute coronary syndrome is an umbrella term describing a group of clinical symptoms associated with chest pain (acute myocardial ischemia) caused by insufficient blood supply to the heart muscle because of clogged arteries. Non-ct-segment elevation acute coronary syndrome is a very common form of this disease, according to the AHA, and is a major cause of emergency care and hospitalization in the United States.

An estimated 1.6 million Americans suffer from an acute coronary syndrome each year. Blumenthal estimates that less than half of these patients get optimal treatment because of the complexity of monitoring and implementing multidrug and lifestyle treatments.

David March | EurekAlert!
Further information:
http://www.jhmi.edu
http://jama.ama-assn.org/
http://www.hopkinsmedicine.org/cardiology/faculty.cfm

More articles from Health and Medicine:

nachricht One gene closer to regenerative therapy for muscular disorders
01.06.2017 | Cincinnati Children's Hospital Medical Center

nachricht The gut microbiota plays a key role in treatment with classic diabetes medication
01.06.2017 | University of Gothenburg

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Climate satellite: Tracking methane with robust laser technology

Heatwaves in the Arctic, longer periods of vegetation in Europe, severe floods in West Africa – starting in 2021, scientists want to explore the emissions of the greenhouse gas methane with the German-French satellite MERLIN. This is made possible by a new robust laser system of the Fraunhofer Institute for Laser Technology ILT in Aachen, which achieves unprecedented measurement accuracy.

Methane is primarily the result of the decomposition of organic matter. The gas has a 25 times greater warming potential than carbon dioxide, but is not as...

Im Focus: How protons move through a fuel cell

Hydrogen is regarded as the energy source of the future: It is produced with solar power and can be used to generate heat and electricity in fuel cells. Empa researchers have now succeeded in decoding the movement of hydrogen ions in crystals – a key step towards more efficient energy conversion in the hydrogen industry of tomorrow.

As charge carriers, electrons and ions play the leading role in electrochemical energy storage devices and converters such as batteries and fuel cells. Proton...

Im Focus: A unique data centre for cosmological simulations

Scientists from the Excellence Cluster Universe at the Ludwig-Maximilians-Universität Munich have establised "Cosmowebportal", a unique data centre for cosmological simulations located at the Leibniz Supercomputing Centre (LRZ) of the Bavarian Academy of Sciences. The complete results of a series of large hydrodynamical cosmological simulations are available, with data volumes typically exceeding several hundred terabytes. Scientists worldwide can interactively explore these complex simulations via a web interface and directly access the results.

With current telescopes, scientists can observe our Universe’s galaxies and galaxy clusters and their distribution along an invisible cosmic web. From the...

Im Focus: Scientists develop molecular thermometer for contactless measurement using infrared light

Temperature measurements possible even on the smallest scale / Molecular ruby for use in material sciences, biology, and medicine

Chemists at Johannes Gutenberg University Mainz (JGU) in cooperation with researchers of the German Federal Institute for Materials Research and Testing (BAM)...

Im Focus: Optoelectronic Inline Measurement – Accurate to the Nanometer

Germany counts high-precision manufacturing processes among its advantages as a location. It’s not just the aerospace and automotive industries that require almost waste-free, high-precision manufacturing to provide an efficient way of testing the shape and orientation tolerances of products. Since current inline measurement technology not yet provides the required accuracy, the Fraunhofer Institute for Laser Technology ILT is collaborating with four renowned industry partners in the INSPIRE project to develop inline sensors with a new accuracy class. Funded by the German Federal Ministry of Education and Research (BMBF), the project is scheduled to run until the end of 2019.

New Manufacturing Technologies for New Products

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Plants are networkers

19.06.2017 | Event News

Digital Survival Training for Executives

13.06.2017 | Event News

Global Learning Council Summit 2017

13.06.2017 | Event News

 
Latest News

A new technique isolates neuronal activity during memory consolidation

22.06.2017 | Life Sciences

Plant inspiration could lead to flexible electronics

22.06.2017 | Materials Sciences

A rhodium-based catalyst for making organosilicon using less precious metal

22.06.2017 | Materials Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>