Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:


Simpler ’alphabet’ guidelines for treating acute coronary syndrome reduce risk


A simplified approach to the management of patients with an acute coronary syndrome (chest pain at rest or with mild exertion) can help ensure that precise risk-reducing strategies are followed to the letter by doctors and other caregivers of patients with this medical condition, according to a study by Johns Hopkins researchers.

"Many doctors think existing guidelines are lengthy and complex and therefore difficult to implement in the clinic and at home by patients," says Roger S. Blumenthal, M.D., associate professor of medicine, director of the Ciccarone Preventive Cardiology Center at Johns Hopkins, and senior investigator of the study, published in the Jan. 19 issue of the Journal of the American Medical Association.
The new guidelines are based on those developed by the American College of Cardiology (ACG),the American Heart Association (AHA) and the results of recent clinical trials, and include risk-factor reduction, lifestyle changes and drugs.

To develop the guidelines, the researchers reviewed all of the relevant peer-reviewed medical publications from 1990 to 2004 in order to assess the most effective and safest practices. They conclude that once patients most likely to benefit from either an early invasive or early conservative strategy are identified, a comprehensive management plan following a simple "ABCDE" approach can be applied.

The "alphabet" approach includes "A" for antiplatelet therapy, anticoagulation, angiotensin converting enzyme inhibition, and angiotensin receptor blockade; "B" for beta-blockade and blood pressure control; "C" for cholesterol treatment and cigarette smoking cessation; "D" for diabetes management and diet; and "E" for exercise.

For the study, the researchers focused on one type of coronary artery disease, called non-ct-segment elevation acute coronary syndrome. According to the AHA, acute coronary syndrome is an umbrella term describing a group of clinical symptoms associated with chest pain (acute myocardial ischemia) caused by insufficient blood supply to the heart muscle because of clogged arteries. Non-ct-segment elevation acute coronary syndrome is a very common form of this disease, according to the AHA, and is a major cause of emergency care and hospitalization in the United States.

An estimated 1.6 million Americans suffer from an acute coronary syndrome each year. Blumenthal estimates that less than half of these patients get optimal treatment because of the complexity of monitoring and implementing multidrug and lifestyle treatments.

David March | EurekAlert!
Further information:

More articles from Health and Medicine:

nachricht Resolving the mystery of preeclampsia
21.10.2016 | Universitätsklinikum Magdeburg

nachricht New potential cancer treatment using microwaves to target deep tumors
12.10.2016 | University of Texas at Arlington

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: New 3-D wiring technique brings scalable quantum computers closer to reality

Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.

"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...

Im Focus: Scientists develop a semiconductor nanocomposite material that moves in response to light

In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.

A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...

Im Focus: Diamonds aren't forever: Sandia, Harvard team create first quantum computer bridge

By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.

"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...

Im Focus: New Products - Highlights of COMPAMED 2016

COMPAMED has become the leading international marketplace for suppliers of medical manufacturing. The trade fair, which takes place every November and is co-located to MEDICA in Dusseldorf, has been steadily growing over the past years and shows that medical technology remains a rapidly growing market.

In 2016, the joint pavilion by the IVAM Microtechnology Network, the Product Market “High-tech for Medical Devices”, will be located in Hall 8a again and will...

Im Focus: Ultra-thin ferroelectric material for next-generation electronics

'Ferroelectric' materials can switch between different states of electrical polarization in response to an external electric field. This flexibility means they show promise for many applications, for example in electronic devices and computer memory. Current ferroelectric materials are highly valued for their thermal and chemical stability and rapid electro-mechanical responses, but creating a material that is scalable down to the tiny sizes needed for technologies like silicon-based semiconductors (Si-based CMOS) has proven challenging.

Now, Hiroshi Funakubo and co-workers at the Tokyo Institute of Technology, in collaboration with researchers across Japan, have conducted experiments to...

All Focus news of the innovation-report >>>



Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

Agricultural Trade Developments and Potentials in Central Asia and the South Caucasus

14.10.2016 | Event News

World Health Summit – Day Three: A Call to Action

12.10.2016 | Event News

Latest News

Resolving the mystery of preeclampsia

21.10.2016 | Health and Medicine

Stanford researchers create new special-purpose computer that may someday save us billions

21.10.2016 | Information Technology

From ancient fossils to future cars

21.10.2016 | Materials Sciences

More VideoLinks >>>