Ranitidine could become new treatment for cerebral ischemia
Ranitidine, a widely used substance used as an antihistaminic drug against gastric ulcers, may become a new treatment for cerebral ischemia caused by craneoencephalic infarcts or traumatisms, the third leading cause of deaths in industrialised countries. In experiments with a model of cerebral ischemia using rats, a team from the Institute of Neurosciences of the Universitat Autònoma de Barcelona (Spain) has observed how the presence of ranitidine reduces neuronal death by a quarter. The substance reaches its maximum effect six hours after the lesion has occurred, which will facilitate treatment in real cases with humans.
The scientists of the Institute of Neurosciences at the UAB have studied ranitidine’s effects on an experimental model using neurons from rats’ brains. The cells underwent a lack of oxygen and glucose analogous to that which they suffer, within the brain, when there is a lack of blood flow (what happens when there is a cerebral ischemia) caused by an infarct or a traumatism. When a lesion of this type occurs, the cells either die directly or, in many cases, they becomes victims of a slow programmed death called apoptosis, a kind of "suicide" at a cellular level.
Octavi López Coronado | EurekAlert!
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A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
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The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.
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07.12.2016 | Health and Medicine