Ranitidine, a widely used substance used as an antihistaminic drug against gastric ulcers, may become a new treatment for cerebral ischemia caused by craneoencephalic infarcts or traumatisms, the third leading cause of deaths in industrialised countries. In experiments with an model of cerebral ischemia using rats, a team from the Institute of Neurosciences of the Universitat Autònoma de Barcelona (Spain) has observed how the presence of ranitidine reduces neuronal death by a quarter. The substance reaches its maximum effect six hours after the lesion has occurred, which will facilitate treatment in real cases with humans.
The scientists of the Institute of Neurosciences at the UAB have studied ranitidine’s effects on an experimental model using neurons from rats’ brains. The cells underwent a lack of oxygen and glucose analogous to that which they suffer, within the brain, when there is a lack of blood flow (what happens when there is a cerebral ischemia) caused by an infarct or a traumatism. When a lesion of this type occurs, the cells either die directly or, in many cases, they becomes victims of a slow programmed death called apoptosis, a kind of “suicide” at a cellular level.
The researchers observed that ranitidine acts preferentially on the neurons that are in the process of apopotosis, and conclusively reduces the percentage of cells that die. Even when treatment is initiated six hours after the lack of oxygen and glucose, and maintaining it over a 24-hour period, this substance reduces by a quarter the number cells that die with respect to the number of cells that die when there is no treatment.
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Physicists of the University of Würzburg have made an astonishing discovery in a specific type of topological insulators. The effect is due to the structure of the materials used. The researchers have now published their work in the journal Science.
Topological insulators are currently the hot topic in physics according to the newspaper Neue Zürcher Zeitung. Only a few weeks ago, their importance was...
In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.
Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...
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A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...
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