Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Bone marrow fat may indicate bone weakening

07.12.2004


Measuring bone marrow fat (BMF) along with bone mineral density (BMD) can better predict weakening of bones than either test done alone, a new study indicates. BMD measurement with DEXA is presently the most commonly used parameter for determining bone weakening. Researchers have long questioned whether there may be other measurable bone components that influence mechanical stability of bone.



The study, conducted by researchers at Georgetown University Hospital in Washington DC, showed that increased BMF is an independent marker of bone weakening. MR spectroscopy was used to gauge BMF non-invasively. MR spectroscopy is a relatively new technique that can be done in conjunction with a spine MRI. This is a pilot study that included 26 patients who underwent both DEXA and MR spectroscopy of the lumbar spine, said Dieter Schellinger, MD, author of the study. Fifteen had normal appearing spine vertebra and eleven showed signs of bone weakening.

When the results of DEXA and MR spectroscopy tests were compared, the ratio of BMF to BMD was "a significant diagnostic indicator of bone weakening," said Dr. Schellinger. The ratio was higher in healthy people and lower in those with signs of bone weakening, he said.


Dr. Schellinger said that other researchers have previously suspected that increased bone fat content represent a bone risk factor. However, before MR spectroscopy, doctors needed to examine bone fat by operatively removing bone samples from patients. A non-invasive method such as MR spectroscopy opens new diagnostic opportunities, he said.

If these results are confirmed by larger studies, increased fat accumulation in bone could be treated with new medications, in an effort to avoid further bone weakening, Dr. Schellinger said.

Jason Ocker | EurekAlert!
Further information:
http://www.arrs.org

More articles from Health and Medicine:

nachricht New malaria analysis method reveals disease severity in minutes
14.08.2017 | University of British Columbia

nachricht New type of blood cells work as indicators of autoimmunity
14.08.2017 | Instituto de Medicina Molecular

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Fizzy soda water could be key to clean manufacture of flat wonder material: Graphene

Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.

As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...

Im Focus: Exotic quantum states made from light: Physicists create optical “wells” for a super-photon

Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.

Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...

Im Focus: Circular RNA linked to brain function

For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.

While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...

Im Focus: RAVAN CubeSat measures Earth's outgoing energy

An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.

The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...

Im Focus: Scientists shine new light on the “other high temperature superconductor”

A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.

Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Call for Papers – ICNFT 2018, 5th International Conference on New Forming Technology

16.08.2017 | Event News

Sustainability is the business model of tomorrow

04.08.2017 | Event News

Clash of Realities 2017: Registration now open. International Conference at TH Köln

26.07.2017 | Event News

 
Latest News

A Map of the Cell’s Power Station

18.08.2017 | Life Sciences

Engineering team images tiny quasicrystals as they form

18.08.2017 | Physics and Astronomy

Researchers printed graphene-like materials with inkjet

18.08.2017 | Materials Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>