USC study finds differences in survival according to lymphoma type in post-HAART era
When it comes to treating HIV-positive patients with blood cancers, not all lymphomas are created equal, according to hematologists from the University of Southern California. Although physicians have treated all types of lymphomas in HIV/AIDS patients with the same drug regimens, researchers from the USC/Norris Comprehensive Cancer Center and Hospital say the drugs are significantly more effective in patients with diffuse large-cell lymphoma, or DLCL, than in patients with small non-cleaved, or SNC, lymphoma. The findings, reported at the 46th Annual Meeting of the American Society of Hematology, suggest that researchers rethink the practice of using the same uniform treatment for everyone with AIDS-related lymphomas.
"Lymphoma is not one disease, but rather represents a group of over 30 different entities. Even lymphomas that were thought to be quite uniform and homogeneous are now recognized as being made up of different variations or sub-types. It will be important for scientists and physicians to recognize these various types, since optimal therapy in the future will probably differ for these sub-types of disease," says senior author Alexandra M. Levine, M.D., Distinguished Professor of Medicine, chief of hematology at the Keck School of Medicine of USC and medical director of the USC/Norris Cancer Hospital.
Sarah Huoh | EurekAlert!
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Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.
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Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.
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In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...
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