The Spanish Pediatrics Association has recently awarded the Pediatrics laboratory at the University of Navarre for a research into tobacco and foetal genetic instability. The study, by Marta Zalacaín, was carried out in conjunction with the Department of Gynacology and Obstetrics at the Hospital Virgen del Camino. “It involved analysing umbilical cords from many births which took place at both centres over three years and which have been distributed in four groups: non-smoking mothers, ex-smokers, those who stop smoking during pregnancy and those who continue to smoke. The aim was the look for any instability in the cord blood to see if there was any relationship with the smoking habits of the mother, either active or passive. In order to carry out this study, the collaboration by the Hospital Virgen del Camino has provided us with a very wide-ranging population of smoking mothers”, explains Marta Zalacaín. The research involved a questionnaire filled in by both the mother and father regarding their smoking habits, together with biochemical tests to measure cotinine in urine, the metabolite produced by nicotine in the body.
This work involves the micronuclei testing, the technology of which has been developed and applied successfully by Marta Zalacaín. According to Dr. Patiño, “When a genotoxic agent affects the cells, such as benzoapyrene in tobacco, genetic damage may be caused which interfere with cell division. As a product of this damage, a number of chromosomic fragments separate from the main nucleus and come together in a secondary nucleus known as a micronucleus. The research is aimed at seeing how the number of micronuclei vary amongst smoking and non-smoking mothers”.
GLUT5 fluorescent probe fingerprints cancer cells
20.04.2018 | Michigan Technological University
Scientists re-create brain neurons to study obesity and personalize treatment
20.04.2018 | Cedars-Sinai Medical Center
University of Connecticut researchers have created a biodegradable composite made of silk fibers that can be used to repair broken load-bearing bones without the complications sometimes presented by other materials.
Repairing major load-bearing bones such as those in the leg can be a long and uncomfortable process.
Study published in the journal ACS Applied Materials & Interfaces is the outcome of an international effort that included teams from Dresden and Berlin in Germany, and the US.
Scientists at the Helmholtz-Zentrum Dresden-Rossendorf (HZDR) together with colleagues from the Helmholtz-Zentrum Berlin (HZB) and the University of Virginia...
Novel highly efficient and brilliant gamma-ray source: Based on model calculations, physicists of the Max PIanck Institute for Nuclear Physics in Heidelberg propose a novel method for an efficient high-brilliance gamma-ray source. A giant collimated gamma-ray pulse is generated from the interaction of a dense ultra-relativistic electron beam with a thin solid conductor. Energetic gamma-rays are copiously produced as the electron beam splits into filaments while propagating across the conductor. The resulting gamma-ray energy and flux enable novel experiments in nuclear and fundamental physics.
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Stable joint cartilage can be produced from adult stem cells originating from bone marrow. This is made possible by inducing specific molecular processes occurring during embryonic cartilage formation, as researchers from the University and University Hospital of Basel report in the scientific journal PNAS.
Certain mesenchymal stem/stromal cells from the bone marrow of adults are considered extremely promising for skeletal tissue regeneration. These adult stem...
In the fight against cancer, scientists are developing new drugs to hit tumor cells at so far unused weak points. Such a “sore spot” is the protein complex...
13.04.2018 | Event News
12.04.2018 | Event News
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20.04.2018 | Physics and Astronomy
20.04.2018 | Interdisciplinary Research
20.04.2018 | Physics and Astronomy