Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Anorexia and bone mass

25.11.2004


A multidisciplinary paediatrics research team has been awarded the “Amagoia” prize by the Sociedad Vasco-Navarra de Pediatría for its work, “Study of bone mass and its determinant factors in female children and adolescents affected by eating habit disorders”. The research was led by Dr. Cristina Azcona, responsible for the Paediatric Endocrinology Unit at the Department of paediatrics at the University Hospital in Navarre.



The patients affected by eating habit disorders are at greater risk from developing osteopenia and osteoporosis compared to the healthy population, mainly due to their state of malnutrition and hypogonadism. The aim of this research was to measure the bone mass in female children and adolescents with eating habit disorders by means of two techniques of measurement: bone densitometry (a technique also known as DEXA or Dual Energy X-ray Absorptiometry) and osteosonography.

The technique conventionally employed to assess bone mass is DEXA although, in recent years, the systems using ultrasounds (such as osteosonography) are being more frequently applied – especially amongst women during menopause. The use of osteosonography in child patients is not widespread as yet. Measurement systems applying this technique generally determine the bone mass in the calcaneum (the great bone of the heel) or the phalanges of the hand. This last system is the one that was used for this research.


It has the advantage of being portable, cheaper than DEXA and does not emit radiation, and so was thought particularly suitable for measuring bone mass in children and adolescents. The process of acquisition of bone mass starts at infancy and, during adolescence, the mineral content of the bone experiences a huge growth - compared to the rates at other stages of growth and child development.

From the perspective of primary prevention it is very important to have non-harmful methods at hand that evaluate bone mass in children given that, if the maximum bone mass is acquired during this period, the risk of suffering fractures during old age is reduced.

Conclusions

The research carried out at the University Hospital shows that, with both techniques for the measurement of bone mass, patients show values inferior to that of healthy children and adolescents. Comparing both techniques, it was observed that, paradoxically, osteosonography is a more suitable technique for the measurement of bone mass in those children and adolescents who have a body composition that is normal for their age, sex and puberal development. “It could be, nevertheless, a complementary method for monitoring the evolution of bone disorder in these patients and thus avoid tests that use radiation, although the DEXA continues to be the reference technique”.

Genetic involvement

The research also studied those determinant factors that may regulate the acquisition of bone mass. To this end, the Pediatrics Laboratory was the centre for the analysis of several polymorphisms of the vitamin D receptor genes, the collagen I-alfa-1 gene and the oestrogens receptor genes that are involved in determining bone mass.

The genetic markers for bone mass can help and identify patients who, because of their genetic make-up, are more prone to getting osteopenia and, in those cases of anorexia nerviosa thereby, may cause more severe complications in the osseous system.

Current treatments do not restore totally the lost bone mass and so, at least, one has to ensure an adequate ingestion of calcium and vitamin D from the outset of the illness.

Garazi Andonegi | alfa
Further information:
http://www.basqueresearch.com
http://www.elhuyar.com

More articles from Health and Medicine:

nachricht World first: Massive thrombosis removed during early pregnancy
20.07.2017 | Universitätsspital Bern

nachricht Therapy of preterm birth in sight?
19.07.2017 | Universitätsspital Bern

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Manipulating Electron Spins Without Loss of Information

Physicists have developed a new technique that uses electrical voltages to control the electron spin on a chip. The newly-developed method provides protection from spin decay, meaning that the contained information can be maintained and transmitted over comparatively large distances, as has been demonstrated by a team from the University of Basel’s Department of Physics and the Swiss Nanoscience Institute. The results have been published in Physical Review X.

For several years, researchers have been trying to use the spin of an electron to store and transmit information. The spin of each electron is always coupled...

Im Focus: The proton precisely weighted

What is the mass of a proton? Scientists from Germany and Japan successfully did an important step towards the most exact knowledge of this fundamental constant. By means of precision measurements on a single proton, they could improve the precision by a factor of three and also correct the existing value.

To determine the mass of a single proton still more accurate – a group of physicists led by Klaus Blaum and Sven Sturm of the Max Planck Institute for Nuclear...

Im Focus: On the way to a biological alternative

A bacterial enzyme enables reactions that open up alternatives to key industrial chemical processes

The research team of Prof. Dr. Oliver Einsle at the University of Freiburg's Institute of Biochemistry has long been exploring the functioning of nitrogenase....

Im Focus: The 1 trillion tonne iceberg

Larsen C Ice Shelf rift finally breaks through

A one trillion tonne iceberg - one of the biggest ever recorded -- has calved away from the Larsen C Ice Shelf in Antarctica, after a rift in the ice,...

Im Focus: Laser-cooled ions contribute to better understanding of friction

Physics supports biology: Researchers from PTB have developed a model system to investigate friction phenomena with atomic precision

Friction: what you want from car brakes, otherwise rather a nuisance. In any case, it is useful to know as precisely as possible how friction phenomena arise –...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

»We are bringing Additive Manufacturing to SMEs«

19.07.2017 | Event News

The technology with a feel for feelings

12.07.2017 | Event News

Leipzig HTP-Forum discusses "hydrothermal processes" as a key technology for a biobased economy

12.07.2017 | Event News

 
Latest News

Researchers create new technique for manipulating polarization of terahertz radiation

20.07.2017 | Information Technology

High-tech sensing illuminates concrete stress testing

20.07.2017 | Materials Sciences

First direct observation and measurement of ultra-fast moving vortices in superconductors

20.07.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>