Anyone who has ever had a urinary tract infection knows that they can be difficult to fight.
The bacterium E. coli is responsible for about 80 percent of human urinary tract infections. Scientists at the University of California, Santa Barbara have made important strides in understanding E. coli at the molecular level in an effort to discover the mechanisms by which E. coli cause urinary tract infections. The findings, the result of two years of study, are published in the November 19 issue of the journal Molecular Cell.
In this study, the scientists –– all associated with the Department of Molecular, Cellular and Developmental Biology –– focused on the mechanisms by which these bacteria, which normally live in the bowel, adhere to and colonize the urinary tract.
Gail Gallessich | EurekAlert!
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Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.
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At TU Wien, an alternative for resource intensive formwork for the construction of concrete domes was developed. It is now used in a test dome for the Austrian Federal Railways Infrastructure (ÖBB Infrastruktur).
Concrete shells are efficient structures, but not very resource efficient. The formwork for the construction of concrete domes alone requires a high amount of...
Many pathogens use certain sugar compounds from their host to help conceal themselves against the immune system. Scientists at the University of Bonn have now, in cooperation with researchers at the University of York in the United Kingdom, analyzed the dynamics of a bacterial molecule that is involved in this process. They demonstrate that the protein grabs onto the sugar molecule with a Pac Man-like chewing motion and holds it until it can be used. Their results could help design therapeutics that could make the protein poorer at grabbing and holding and hence compromise the pathogen in the host. The study has now been published in “Biophysical Journal”.
The cells of the mouth, nose and intestinal mucosa produce large quantities of a chemical called sialic acid. Many bacteria possess a special transport system...
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