Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Prevalence of Human Papillomavirus Infection Differs for Men and Women

17.11.2004


The age-specific prevalence of sexually transmitted human papillomavirus infection in women differs substantially from that in men who have sex with men, according to a new study published in the December 15 issue of The Journal of Infectious Diseases, now available online. The study, led by Peter V. Chin-Hong of the University of California, San Francisco, indicates a high prevalence of anal human papillomavirus (HPV) infection in all age groups of men who have sex with men. This finding contrasts with the age-related prevalence of cervical HPV infection.



Numerous studies have previously documented a causal link between HPV infection and anal and cervical cancers. Many studies have also shown that cervical HPV infection is strongly related to age, peaking early and falling after age 30. Little, however, is known about the age-specific prevalence of anal HPV infection in men who have sex with men. Most research on the subject has involved men in a narrow age range who were HIV-infected. The investigators described their study as the first to document anal HPV infection in a HIV-seronegative population of men who have sex with men who were diverse in terms of age and geography.

The study was conducted between January 2001 and October 2002 and involved 1,218 men who have sex with men living in Boston, Denver, New York, and San Francisco. The men were aged 18 to 89 years and 78% were white, 14% were Latino, 6% were African American, and 3% were Asian. The researchers found the prevalence rate of anal HPV infection to be 57%, and this rate did not change with age or from city to city. Factors associated with infection were receptive anal sex and having more than five sex partners in the previous six months.


Study results also described the nature of anal HPV infection in this group. Forty-five percent of those infected had more than one type of HPV. The prevalence of infection with “high-risk” HPV types associated with invasive anal cancer was 26%, suggesting that a high proportion of men who have sex with men may be at risk for anal cancer.

Chin-Hong and colleagues hypothesized that the sex-based difference in HPV epidemiology may reflect a difference between these populations in the number of new sex partners after age 30. They also suggest that there may be organ-specific and hormonal differences that contribute to the epidemiological differences. The investigators noted that one of the strengths of their study was its size and that it is the first multi-city study of anal HPV infection. A potential limitation, they explained, is that they do not know if their results can be generalized to certain subgroups of men who have sex with men, such as those living in rural areas.

“Based on the results of this study, previous assumptions about extrapolating data from cervical disease in women to anal HPV infection in men who have sex with men must be questioned,” Dr. Chin-Hong said. “The unique epidemiology of anal HPV infection should be further explored for its implications for HPV vaccine development and for understanding the risk factors of anal cancer.”

Steve Baragona | EurekAlert!
Further information:
http://www.idsociety.org

More articles from Health and Medicine:

nachricht PET imaging tracks Zika virus infection, disease progression in mouse model
20.09.2017 | US Army Medical Research Institute of Infectious Diseases

nachricht 'Exciting' discovery on path to develop new type of vaccine to treat global viruses
18.09.2017 | University of Southampton

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Tiny lasers from a gallery of whispers

New technique promises tunable laser devices

Whispering gallery mode (WGM) resonators are used to make tiny micro-lasers, sensors, switches, routers and other devices. These tiny structures rely on a...

Im Focus: Ultrafast snapshots of relaxing electrons in solids

Using ultrafast flashes of laser and x-ray radiation, scientists at the Max Planck Institute of Quantum Optics (Garching, Germany) took snapshots of the briefest electron motion inside a solid material to date. The electron motion lasted only 750 billionths of the billionth of a second before it fainted, setting a new record of human capability to capture ultrafast processes inside solids!

When x-rays shine onto solid materials or large molecules, an electron is pushed away from its original place near the nucleus of the atom, leaving a hole...

Im Focus: Quantum Sensors Decipher Magnetic Ordering in a New Semiconducting Material

For the first time, physicists have successfully imaged spiral magnetic ordering in a multiferroic material. These materials are considered highly promising candidates for future data storage media. The researchers were able to prove their findings using unique quantum sensors that were developed at Basel University and that can analyze electromagnetic fields on the nanometer scale. The results – obtained by scientists from the University of Basel’s Department of Physics, the Swiss Nanoscience Institute, the University of Montpellier and several laboratories from University Paris-Saclay – were recently published in the journal Nature.

Multiferroics are materials that simultaneously react to electric and magnetic fields. These two properties are rarely found together, and their combined...

Im Focus: Fast, convenient & standardized: New lab innovation for automated tissue engineering & drug

MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems Holding GmbH about commercial use of a multi-well tissue plate for automated and reliable tissue engineering & drug testing.

MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems...

Im Focus: Silencing bacteria

HZI researchers pave the way for new agents that render hospital pathogens mute

Pathogenic bacteria are becoming resistant to common antibiotics to an ever increasing degree. One of the most difficult germs is Pseudomonas aeruginosa, a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

“Lasers in Composites Symposium” in Aachen – from Science to Application

19.09.2017 | Event News

I-ESA 2018 – Call for Papers

12.09.2017 | Event News

EMBO at Basel Life, a new conference on current and emerging life science research

06.09.2017 | Event News

 
Latest News

Molecular Force Sensors

20.09.2017 | Life Sciences

Producing electricity during flight

20.09.2017 | Power and Electrical Engineering

Tiny lasers from a gallery of whispers

20.09.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>