Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Prevalence of Human Papillomavirus Infection Differs for Men and Women

17.11.2004


The age-specific prevalence of sexually transmitted human papillomavirus infection in women differs substantially from that in men who have sex with men, according to a new study published in the December 15 issue of The Journal of Infectious Diseases, now available online. The study, led by Peter V. Chin-Hong of the University of California, San Francisco, indicates a high prevalence of anal human papillomavirus (HPV) infection in all age groups of men who have sex with men. This finding contrasts with the age-related prevalence of cervical HPV infection.



Numerous studies have previously documented a causal link between HPV infection and anal and cervical cancers. Many studies have also shown that cervical HPV infection is strongly related to age, peaking early and falling after age 30. Little, however, is known about the age-specific prevalence of anal HPV infection in men who have sex with men. Most research on the subject has involved men in a narrow age range who were HIV-infected. The investigators described their study as the first to document anal HPV infection in a HIV-seronegative population of men who have sex with men who were diverse in terms of age and geography.

The study was conducted between January 2001 and October 2002 and involved 1,218 men who have sex with men living in Boston, Denver, New York, and San Francisco. The men were aged 18 to 89 years and 78% were white, 14% were Latino, 6% were African American, and 3% were Asian. The researchers found the prevalence rate of anal HPV infection to be 57%, and this rate did not change with age or from city to city. Factors associated with infection were receptive anal sex and having more than five sex partners in the previous six months.


Study results also described the nature of anal HPV infection in this group. Forty-five percent of those infected had more than one type of HPV. The prevalence of infection with “high-risk” HPV types associated with invasive anal cancer was 26%, suggesting that a high proportion of men who have sex with men may be at risk for anal cancer.

Chin-Hong and colleagues hypothesized that the sex-based difference in HPV epidemiology may reflect a difference between these populations in the number of new sex partners after age 30. They also suggest that there may be organ-specific and hormonal differences that contribute to the epidemiological differences. The investigators noted that one of the strengths of their study was its size and that it is the first multi-city study of anal HPV infection. A potential limitation, they explained, is that they do not know if their results can be generalized to certain subgroups of men who have sex with men, such as those living in rural areas.

“Based on the results of this study, previous assumptions about extrapolating data from cervical disease in women to anal HPV infection in men who have sex with men must be questioned,” Dr. Chin-Hong said. “The unique epidemiology of anal HPV infection should be further explored for its implications for HPV vaccine development and for understanding the risk factors of anal cancer.”

Steve Baragona | EurekAlert!
Further information:
http://www.idsociety.org

More articles from Health and Medicine:

nachricht Biofilm discovery suggests new way to prevent dangerous infections
23.05.2017 | University of Texas at Austin

nachricht Another reason to exercise: Burning bone fat -- a key to better bone health
19.05.2017 | University of North Carolina Health Care

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Can the immune system be boosted against Staphylococcus aureus by delivery of messenger RNA?

Staphylococcus aureus is a feared pathogen (MRSA, multi-resistant S. aureus) due to frequent resistances against many antibiotics, especially in hospital infections. Researchers at the Paul-Ehrlich-Institut have identified immunological processes that prevent a successful immune response directed against the pathogenic agent. The delivery of bacterial proteins with RNA adjuvant or messenger RNA (mRNA) into immune cells allows the re-direction of the immune response towards an active defense against S. aureus. This could be of significant importance for the development of an effective vaccine. PLOS Pathogens has published these research results online on 25 May 2017.

Staphylococcus aureus (S. aureus) is a bacterium that colonizes by far more than half of the skin and the mucosa of adults, usually without causing infections....

Im Focus: A quantum walk of photons

Physicists from the University of Würzburg are capable of generating identical looking single light particles at the push of a button. Two new studies now demonstrate the potential this method holds.

The quantum computer has fuelled the imagination of scientists for decades: It is based on fundamentally different phenomena than a conventional computer....

Im Focus: Turmoil in sluggish electrons’ existence

An international team of physicists has monitored the scattering behaviour of electrons in a non-conducting material in real-time. Their insights could be beneficial for radiotherapy.

We can refer to electrons in non-conducting materials as ‘sluggish’. Typically, they remain fixed in a location, deep inside an atomic composite. It is hence...

Im Focus: Wafer-thin Magnetic Materials Developed for Future Quantum Technologies

Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.

Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...

Im Focus: World's thinnest hologram paves path to new 3-D world

Nano-hologram paves way for integration of 3-D holography into everyday electronics

An Australian-Chinese research team has created the world's thinnest hologram, paving the way towards the integration of 3D holography into everyday...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Marine Conservation: IASS Contributes to UN Ocean Conference in New York on 5-9 June

24.05.2017 | Event News

AWK Aachen Machine Tool Colloquium 2017: Internet of Production for Agile Enterprises

23.05.2017 | Event News

Dortmund MST Conference presents Individualized Healthcare Solutions with micro and nanotechnology

22.05.2017 | Event News

 
Latest News

How herpesviruses win the footrace against the immune system

26.05.2017 | Life Sciences

Water forms 'spine of hydration' around DNA, group finds

26.05.2017 | Life Sciences

First Juno science results supported by University of Leicester's Jupiter 'forecast'

26.05.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>