Researchers working with Florida red tide discovered two new compounds that may treat mucus build-up associated with cystic fibrosis and similar lung diseases. Preliminary studies show these compounds improve the flow of mucus through the respiratory tract, allowing airways to clear more quickly and efficiently.
"These compounds are excellent candidates for the development of an entirely new class of drugs targeted for the treatment of mucociliary disease," said Kenneth Olden, Ph.D., director of the National Institute of Environmental Health Sciences.
The NIEHS, one of the National Institutes of Health, provided $6.6 million to scientists at the University of North Carolina at Wilmington and Mount Sinai Medical Center in Miami Beach for the study. The findings are published in the January issue of the American Journal of Respiratory and Critical Care Medicine. Florida red tide consists of microscopic plant-like cells that produce a potent chemical toxin that causes fish kills, contaminates shellfish, and creates severe respiratory irritation in people. As the concentration of red tide increases, waves and wind disperse toxin particles into the air, causing irritation of the eyes, nose, throat, lips and tongue.
John Peterson | EurekAlert!
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