The closer hospitals adhere to national guidelines for treating potential heart attack patients, the greater the decline in their mortality rates, according to a analysis of treatment patterns at 315 U.S. hospitals by Duke Clinical Research Institute researchers.
The analysis is among the first of its kind to definitively link hospitals improvement in use of guideline-recommended treatments with concomitant reductions in hospital death rates. These findings should provide compelling scientific evidence that quality improvement initiatives are worth it, and translate into significant savings in patients lives, the researchers said. "These findings should be a strong motivation to people, who until now found it difficult to commit to quality improvement initiatives without evidence that they work," said cardiologist Eric Peterson, M.D., who presented the results of the Duke analysis Nov. 10, 2004, at the annual scientific sessions of American Heart Association (AHA) in New Orleans. "This study shows what a profound influence quality improvement can have on saving patients lives."
The study involved analyzing reports of hospitals adherence to treatment guidelines and mortality rates over a two-year period, from 2002 to 2003. "When we looked at the hospitals as a group at the beginning, they were almost indistinguishable from each other in their capabilities and services offered," said Peterson "The only difference was that over time some changed their practices according to the guidelines and others did not. "However, when we then looked at how mortality rates changed from baseline to the latest quarter, what we found was remarkable," he continued. "Those hospitals that were the worst at following the guidelines saw their mortality rates increase, while those hospitals that had the largest improvement in adherence had the greatest decrease in mortality rates. We believe this is the best argument for hospitals to devote the necessary time and effort into improving their systems for taking care of these patients."
Richard Merritt | EurekAlert!
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Plants and algae use the enzyme Rubisco to fix carbon dioxide, removing it from the atmosphere and converting it into biomass. Algae have figured out a way to increase the efficiency of carbon fixation. They gather most of their Rubisco into a ball-shaped microcompartment called the pyrenoid, which they flood with a high local concentration of carbon dioxide. A team of scientists at Princeton University, the Carnegie Institution for Science, Stanford University and the Max Plank Institute of Biochemistry have unravelled the mysteries of how the pyrenoid is assembled. These insights can help to engineer crops that remove more carbon dioxide from the atmosphere while producing more food.
A warming planet
Our brains house extremely complex neuronal circuits, whose detailed structures are still largely unknown. This is especially true for the so-called cerebral cortex of mammals, where among other things vision, thoughts or spatial orientation are being computed. Here the rules by which nerve cells are connected to each other are only partly understood. A team of scientists around Moritz Helmstaedter at the Frankfiurt Max Planck Institute for Brain Research and Helene Schmidt (Humboldt University in Berlin) have now discovered a surprisingly precise nerve cell connectivity pattern in the part of the cerebral cortex that is responsible for orienting the individual animal or human in space.
The researchers report online in Nature (Schmidt et al., 2017. Axonal synapse sorting in medial entorhinal cortex, DOI: 10.1038/nature24005) that synapses in...
Whispering gallery mode (WGM) resonators are used to make tiny micro-lasers, sensors, switches, routers and other devices. These tiny structures rely on a...
Using ultrafast flashes of laser and x-ray radiation, scientists at the Max Planck Institute of Quantum Optics (Garching, Germany) took snapshots of the briefest electron motion inside a solid material to date. The electron motion lasted only 750 billionths of the billionth of a second before it fainted, setting a new record of human capability to capture ultrafast processes inside solids!
When x-rays shine onto solid materials or large molecules, an electron is pushed away from its original place near the nucleus of the atom, leaving a hole...
For the first time, physicists have successfully imaged spiral magnetic ordering in a multiferroic material. These materials are considered highly promising candidates for future data storage media. The researchers were able to prove their findings using unique quantum sensors that were developed at Basel University and that can analyze electromagnetic fields on the nanometer scale. The results – obtained by scientists from the University of Basel’s Department of Physics, the Swiss Nanoscience Institute, the University of Montpellier and several laboratories from University Paris-Saclay – were recently published in the journal Nature.
Multiferroics are materials that simultaneously react to electric and magnetic fields. These two properties are rarely found together, and their combined...
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