Trials have raised questions on the current management and standard of care for advanced ovarian cancer (AOC). These controversies highlight implications for future clinical research and policy-making, as reviewed in an article published in the International Journal of Gynecological Cancer.
According to the paper, ovarian cancer is one of the leading causes of cancer-related death in women though unfortunately, the disease is only diagnosed at advanced stages. This study, led by Max S. Mano, Consultant Medical Oncologist, critically analyzes and highlights potential caveats in the controversial issues involved in AOC management.
Surgery, chemotherapy, dosage and duration are among the topics reviewed to “reconstruct the development of the current standard first-line therapy for AOC” due to the crucial questions remaining regarding optimal management even after research has moved forward. Such questions include whether the doublet platinum-cyclophosphamide, used in chemotherapy, was actually the best comparator for now standard platinum-paclitaxel; also questioned was the potential of higher doses.
Sharon Agsalda | alfa
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University of Connecticut researchers have created a biodegradable composite made of silk fibers that can be used to repair broken load-bearing bones without the complications sometimes presented by other materials.
Repairing major load-bearing bones such as those in the leg can be a long and uncomfortable process.
Study published in the journal ACS Applied Materials & Interfaces is the outcome of an international effort that included teams from Dresden and Berlin in Germany, and the US.
Scientists at the Helmholtz-Zentrum Dresden-Rossendorf (HZDR) together with colleagues from the Helmholtz-Zentrum Berlin (HZB) and the University of Virginia...
Novel highly efficient and brilliant gamma-ray source: Based on model calculations, physicists of the Max PIanck Institute for Nuclear Physics in Heidelberg propose a novel method for an efficient high-brilliance gamma-ray source. A giant collimated gamma-ray pulse is generated from the interaction of a dense ultra-relativistic electron beam with a thin solid conductor. Energetic gamma-rays are copiously produced as the electron beam splits into filaments while propagating across the conductor. The resulting gamma-ray energy and flux enable novel experiments in nuclear and fundamental physics.
The typical wavelength of light interacting with an object of the microcosm scales with the size of this object. For atoms, this ranges from visible light to...
Stable joint cartilage can be produced from adult stem cells originating from bone marrow. This is made possible by inducing specific molecular processes occurring during embryonic cartilage formation, as researchers from the University and University Hospital of Basel report in the scientific journal PNAS.
Certain mesenchymal stem/stromal cells from the bone marrow of adults are considered extremely promising for skeletal tissue regeneration. These adult stem...
In the fight against cancer, scientists are developing new drugs to hit tumor cells at so far unused weak points. Such a “sore spot” is the protein complex...
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