Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

RFA safe for treating liver tumors pushing on GI tract; Alcohol injection makes RFA more effective

04.11.2004


Radiofrequency ablation (RFA), the use of electrodes to heat and destroy abnormal tissue, is a safe and effective treatment for eradicating liver tumors that are in contact with the gastrointestinal (GI) tract, says one study in the November 2004 issue of the American Journal of Roentgenology, while a separate study in that same issue says that RFA becomes even more effective when alcohol is injected into a liver tumor before an RFA procedure.



In the first study, researchers from the Samsung Medical Center in Seoul, South Korea, analyzed 41 patients who each had a liver tumor abutting the GI tract. RFA was performed on these patients and, upon follow-up, 34 of the 41 tumors were found to be eradicated, with no bowel-related complications occurring in any of the 41 patients.

According to Hyo K. Lim, MD, one of the authors of the study, RFA is considered a safe treatment for liver tumors, but investigators have warned against injuries that might occur when the tumors are touching the GI tract. "Many investigators have cautioned that RFA of tumors abutting the bowel could result in collateral thermal damage to the bowel. Also, there is potential for the tines of the electrode to perforate the bowel." According to the study’s results, however, this isn’t the case, said Dr. Lim.


In a separate study, researchers from Brigham and Women’s Hospital in Boston, MA, found that injecting alcohol into a liver tumor immediately prior to RFA makes the RFA procedure more effective.

For that study, the researchers compared one group of patients who underwent RFA alone to a second group who underwent a combination of RFA and alcohol injection. The researchers found that by adding alcohol injections to RFA, more of the tumor was destroyed with each treatment, so patients had to undergo fewer RFA treatments. "These results suggest that the combination could lead to more effective treatment of liver tumors, particularly with large tumors," said Sridhar Shankar, MD, lead author of the study, who is currently at the University of Massachusetts, Worcester.

According to the researchers, the combination of alcohol injection and RFA is also effective in tumors in other parts of the body, as well. "We have used the combination therapy successfully in other parts of the body, such as with bone and soft-tissue tumors. However, the combination must be used carefully in areas where alcohol leakage could be deleterious, such as in the lung where normal tissue may be affected," said Dr. Shankar.

Jason Ocker | EurekAlert!
Further information:
http://www.arrs.org

More articles from Health and Medicine:

nachricht Malaria Already Endemic in the Mediterranean by the Roman Period
27.07.2017 | Universität Zürich

nachricht Serious children’s infections also spreading in Switzerland
26.07.2017 | Universitätsspital Bern

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Physicists Design Ultrafocused Pulses

Physicists working with researcher Oriol Romero-Isart devised a new simple scheme to theoretically generate arbitrarily short and focused electromagnetic fields. This new tool could be used for precise sensing and in microscopy.

Microwaves, heat radiation, light and X-radiation are examples for electromagnetic waves. Many applications require to focus the electromagnetic fields to...

Im Focus: Carbon Nanotubes Turn Electrical Current into Light-emitting Quasi-particles

Strong light-matter coupling in these semiconducting tubes may hold the key to electrically pumped lasers

Light-matter quasi-particles can be generated electrically in semiconducting carbon nanotubes. Material scientists and physicists from Heidelberg University...

Im Focus: Flexible proximity sensor creates smart surfaces

Fraunhofer IPA has developed a proximity sensor made from silicone and carbon nanotubes (CNT) which detects objects and determines their position. The materials and printing process used mean that the sensor is extremely flexible, economical and can be used for large surfaces. Industry and research partners can use and further develop this innovation straight away.

At first glance, the proximity sensor appears to be nothing special: a thin, elastic layer of silicone onto which black square surfaces are printed, but these...

Im Focus: 3-D scanning with water

3-D shape acquisition using water displacement as the shape sensor for the reconstruction of complex objects

A global team of computer scientists and engineers have developed an innovative technique that more completely reconstructs challenging 3D objects. An ancient...

Im Focus: Manipulating Electron Spins Without Loss of Information

Physicists have developed a new technique that uses electrical voltages to control the electron spin on a chip. The newly-developed method provides protection from spin decay, meaning that the contained information can be maintained and transmitted over comparatively large distances, as has been demonstrated by a team from the University of Basel’s Department of Physics and the Swiss Nanoscience Institute. The results have been published in Physical Review X.

For several years, researchers have been trying to use the spin of an electron to store and transmit information. The spin of each electron is always coupled...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Clash of Realities 2017: Registration now open. International Conference at TH Köln

26.07.2017 | Event News

Closing the Sustainability Circle: Protection of Food with Biobased Materials

21.07.2017 | Event News

»We are bringing Additive Manufacturing to SMEs«

19.07.2017 | Event News

 
Latest News

Programming cells with computer-like logic

27.07.2017 | Life Sciences

Identified the component that allows a lethal bacteria to spread resistance to antibiotics

27.07.2017 | Life Sciences

Malaria Already Endemic in the Mediterranean by the Roman Period

27.07.2017 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>