Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Electroconvulsive therapy improves mood, quality of life

02.11.2004


Electroconvulsive therapy (ECT) improves mood, quality of life and activities of daily living in patients with major depression, according to researchers at Wake Forest University Baptist Medical Center, "Quality of life and function are improved in ECT patients as early as two weeks after the conclusion of ECT," said Vaughn McCall, M.D., professor and chairman of the Department of Psychiatry and Behavioral Medicine and the lead author, writing in the November issue of the British Journal of Psychiatry.



ECT is a treatment for severe mental illness, especially major depression, in which a brief application of electric stimulus – a shock – is used to produce a generalized seizure. "ECT produces a net improvement in health for most patients, and should help fill the knowledge gap that recently led to more restrictive guidance on the use of ECT in the United Kingdom," said McCall. "A restrictive attitude toward ECT is not warranted."

Britain’s National Institute of Clinical Excellence (NICE) last year recommended sharp restrictions on the use of electroconvulsive therapy "until more information is available about ECT’s effect on memory, quality of life and other pertinent health outcomes."


NICE, an arm of Britain’s National Health Service, said ECT should be used "only to achieve rapid and short-term improvements of severe symptoms after other treatment options have failed and/or when the condition is considered to be potentially life threatening in individuals with severe depressive illness, catatonia or a prolonged or severe manic episode."

The study at Wake Forest Baptist included 77 patients with major depression, and the effects of depression were confirmed by use of several psychiatric measuring scales, some answered by the patients and some by clinicians. These tests were completed before and immediately after ECT and again at two weeks and four weeks after ECT.

McCall said that 66 percent of the patients showed improvement after ECT. "The sample showed improvement in most measures of mood, cognition, quality of life and function" at both two weeks and four weeks after ECT, he said. The only decline was on an autobiographical memory test, but that test is designed to measure only memory loss, not improvement.

When he compared test results on nine of 10 psychological scales before ECT with the same tests repeated at both two and four weeks after ECT, the differences were statistically significant, meaning that they could not have happened by chance.

McCall said the new study confirmed earlier results at Wake Forest Baptist that function and quality of life improve after ECT "to a greater extent than medication-treated patients," but, he said, the prior study’s first measurement was not made until four weeks after ECT. McCall said the change in quality of life was largely related to changes in mood.

But there also was improvement on various measurements of cognition and especially of memory. "Although the improvement on neurological tests could be attributed to a practice effect [taking the same test several times], it is equally likely that they represent true improvements in cognitive efficiency," he said.

Also involved in the study were Peter B. Rosenquist, M.D., associate professor of psychiatry, and Aaron Dunn, B.A., an associate project manager in the Psychiatry Department.

Karen Richardson | EurekAlert!
Further information:
http://www.wfubmc.edu

More articles from Health and Medicine:

nachricht NTU scientists build new ultrasound device using 3-D printing technology
07.12.2016 | Nanyang Technological University

nachricht How to turn white fat brown
07.12.2016 | University of Pennsylvania School of Medicine

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Significantly more productivity in USP lasers

In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.

Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...

Im Focus: Shape matters when light meets atom

Mapping the interaction of a single atom with a single photon may inform design of quantum devices

Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...

Im Focus: Novel silicon etching technique crafts 3-D gradient refractive index micro-optics

A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.

Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...

Im Focus: Quantum Particles Form Droplets

In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.

“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...

Im Focus: MADMAX: Max Planck Institute for Physics takes up axion research

The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.

The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ICTM Conference 2017: Production technology for turbomachine manufacturing of the future

16.11.2016 | Event News

Innovation Day Laser Technology – Laser Additive Manufacturing

01.11.2016 | Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

 
Latest News

NTU scientists build new ultrasound device using 3-D printing technology

07.12.2016 | Health and Medicine

The balancing act: An enzyme that links endocytosis to membrane recycling

07.12.2016 | Life Sciences

How to turn white fat brown

07.12.2016 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>