Postmenopausal women who take combination estrogen-plus-progestin hormone-replacement therapy for one year experience a twofold increase in breast density – a known risk factor for breast cancer – and a quadrupled risk of having an abnormal mammogram, according to new findings from a sub-study of the Womens Health Initiative, or WHI.
Lead investigator Anne McTiernan, M.D., Ph.D., of Fred Hutchinson Cancer Research Center, presented these findings today at the third annual International Conference on Frontiers in Cancer Prevention Research hosted by the American Association for Cancer Research. "I was surprised by the magnitude of the effect – the doubling of breast density associated with combination-hormone therapy," said McTiernan, a member of Fred Hutchinsons Public Health Sciences Division and lead physician of the WHI Clinical Coordinating Center, which is based at Fred Hutchinson.
The effect of HRT on breast density remained consistent throughout the two-year study period and was similar across ethnic and racial groups. The impact was particularly pronounced among women in the highest age bracket; those between 70 and 79 experienced a nearly threefold increase in breast density as compared to younger women, presumably because their breast tissue was less dense to begin with, McTiernan said. "These findings are unique in showing a sustained effect over two years and that even in older postmenpausal women breast density can increase in response to estrogen-plus-progestin therapy," McTiernan said.
Warren Froelich | EurekAlert!
The end of pneumonia? New vaccine offers hope
23.10.2017 | University at Buffalo
Scientists track ovarian cancers to site of origin: Fallopian tubes
23.10.2017 | Johns Hopkins Medicine
Salmonellae are dangerous pathogens that enter the body via contaminated food and can cause severe infections. But these bacteria are also known to target...
University of Maryland researchers contribute to historic detection of gravitational waves and light created by event
On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...
Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.
Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....
Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).
When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...
Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.
How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...
23.10.2017 | Event News
17.10.2017 | Event News
10.10.2017 | Event News
23.10.2017 | Life Sciences
23.10.2017 | Physics and Astronomy
23.10.2017 | Health and Medicine