Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Muscle-building hand-grips aid systolic blood pressure, carotid AD, endothelial function

07.10.2004


High-tech isometrics helps persons on hypertension medication

Don’t try this at home, but a high-tech version of the muscle crowd’s hand-grip has demonstrated the ability to lower blood pressure, improve the flexibility of the carotid artery and heighten vasoactive sensitivity in people taking medication for hypertension.

Two studies at the McMaster University Department of Kinesiology Exercise and Metabolism Research Group sought to confirm earlier findings related to risk factors for cardiovascular disease (CVD), as well as to uncover some of the underlying mechanisms. Both studies used similar methodology and isometric handgrip (IHG) exercise three times a week for eight weeks at 30% of maximal voluntary contraction.



IHG’s effect on carotid distensibility

Adrienne Visocchi led a group studying whether arterial distensibility (AD, or the ability of arteries to stretch) contributed to the reduction in resting blood pressure (RBP). They compared the impact of isometric arm and leg exercise on RBP as well as central (carotid) and peripheral (arm and leg arteries) AD in persons who were already taking medication for hypertension, or high blood pressure. Her group consisted of Cheri L.M. McGowan, Martha Faulkner, Robin Verduyn, Neil McCartney and Maureen J. MacDonald.

Results indicated that following IHG exercise systolic blood pressure decreased significantly, while carotid AD improved significantly. IHG didn’t affect either diastolic BP or peripheral AD. The study also tested isometric leg press exercise, but it had no effect on any of the parameters being studied.

IHG’s effect on endothelial function

Hypertension is associated with endothelial dysfunction and development of cardiovascular disease, noted Cheri L.M. McGowan, who led the other McMaster study. Her group studied endothelial function after IGH to see if it played a role in the reduction of blood pressure in people taking anti-hypertensive medication. Other group members included Adrienne Viscocchi, Martha Faulkner, Mark Rakobowchuk, Neil McCartney and Maureen J. MacDonald. Both McMaster studies were undertaken in Dr. MacDonald’s laboratory.

Prior to beginning the exercise regimen, vascular reactivity, which is a measure of an artery’s ability to dilate in response to an increase in blood flow, was measured in both arms using a technique called flow-mediated dilation (FMD). This technique involves stopping blood flow to the forearm for 5 minutes then measuring the artery’s internal diameter with ultrasound after blood flow is reintroduced. After training, systolic blood pressure decreased significantly, while FMD increased (both relative and normalized to average shear rate). Average resting diameter and resting flow remained unchanged.

The researchers also noted that following training there was a reduced reactive hyperemic flow (blood flow after cuff deflation). Although the amount of blood flowing through the artery was less than before training, the artery still dilated more. This suggests a heightened vasoactive sensitivity to the reactive hyperemic stimulus. These findings suggest that the reduction of blood pressure with IHG may be due to improvements of endothelial function.

Mayer Resnick | EurekAlert!
Further information:
http://www.the-aps.org

More articles from Health and Medicine:

nachricht Fast-tracking T cell therapies with immune-mimicking biomaterials
16.01.2018 | Wyss Institute for Biologically Inspired Engineering at Harvard

nachricht Dengue takes low and slow approach to replication
12.01.2018 | Duke University

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Scientists decipher key principle behind reaction of metalloenzymes

So-called pre-distorted states accelerate photochemical reactions too

What enables electrons to be transferred swiftly, for example during photosynthesis? An interdisciplinary team of researchers has worked out the details of how...

Im Focus: The first precise measurement of a single molecule's effective charge

For the first time, scientists have precisely measured the effective electrical charge of a single molecule in solution. This fundamental insight of an SNSF Professor could also pave the way for future medical diagnostics.

Electrical charge is one of the key properties that allows molecules to interact. Life itself depends on this phenomenon: many biological processes involve...

Im Focus: Paradigm shift in Paris: Encouraging an holistic view of laser machining

At the JEC World Composite Show in Paris in March 2018, the Fraunhofer Institute for Laser Technology ILT will be focusing on the latest trends and innovations in laser machining of composites. Among other things, researchers at the booth shared with the Aachen Center for Integrative Lightweight Production (AZL) will demonstrate how lasers can be used for joining, structuring, cutting and drilling composite materials.

No other industry has attracted as much public attention to composite materials as the automotive industry, which along with the aerospace industry is a driver...

Im Focus: Room-temperature multiferroic thin films and their properties

Scientists at Tokyo Institute of Technology (Tokyo Tech) and Tohoku University have developed high-quality GFO epitaxial films and systematically investigated their ferroelectric and ferromagnetic properties. They also demonstrated the room-temperature magnetocapacitance effects of these GFO thin films.

Multiferroic materials show magnetically driven ferroelectricity. They are attracting increasing attention because of their fascinating properties such as...

Im Focus: A thermometer for the oceans

Measurement of noble gases in Antarctic ice cores

The oceans are the largest global heat reservoir. As a result of man-made global warming, the temperature in the global climate system increases; around 90% of...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

10th International Symposium: “Advanced Battery Power – Kraftwerk Batterie” Münster, 10-11 April 2018

08.01.2018 | Event News

See, understand and experience the work of the future

11.12.2017 | Event News

Innovative strategies to tackle parasitic worms

08.12.2017 | Event News

 
Latest News

Novel 3-D printing technique yields high-performance composites

16.01.2018 | Materials Sciences

New application for acoustics helps estimate marine life populations

16.01.2018 | Life Sciences

Fast-tracking T cell therapies with immune-mimicking biomaterials

16.01.2018 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>