Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Cyberknife radiosurgery is a safe and effective treatment for benign tumors

06.10.2004


Treating benign tumors outside the brain with CyberKnife Frameless Radiosurgery resulted in significant improvement in symptoms and minimal toxicity, according to a study by University of Pittsburgh School of Medicine researchers presented today at the 46th Annual Meeting of the American Society for Therapeutic Radiology and Oncology (ASTRO) in Atlanta.



"While stereotactic radiosurgery for the treatment of benign brain tumors has become widely accepted, our knowledge about the use of this technology for benign tumors outside the brain has been limited," said Steve Burton, M.D., study co-author and assistant professor, department of radiation oncology, University of Pittsburgh School of Medicine. "The results of our study indicate that treating these tumors with CyberKnife is safe and effective and can successfully control their growth and progression."

The study, whose purpose was to evaluate the feasibility, toxicity and local control of patients with symptomatic benign tumors treated with CyberKnife, evaluated 50 benign tumors in 35 patients who underwent radiosurgery between 2001 and 2004 at the University of Pittsburgh Medical Center. The tumors were located in the spine (36), neck (6), skull (3), eye (3) and brainstem (2). Seventy-eight percent of patients treated with CyberKnife experienced an improvement in their pre-treatment symptoms, which included pain and weakness. The local control rate – the rate at which the tumor’s growth was controlled locally – was 96 percent for the 26 patients who underwent follow-up imaging from one to 25 months after the treatment was administered.


"Our findings demonstrate that CyberKnife may offer a promising treatment option for patients with benign tumors who are not candidates for surgery or whose tumors are not amenable to surgery," said Dr. Burton. "The potential benefits are significant and include short-term treatment time in an outpatient setting with rapid recovery and symptomatic response." Dr. Burton added that follow-up studies will seek to assess the long-term tumor control rates as well as any future effects.

"This study represents the largest to date on the use of frameless radiosurgery to treat benign extra-cranial lesions, and the results thus far are very encouraging. Of noteworthy interest, CyberKnife was able to control aggressive benign tumors that had progressed despite surgery and/or conventional radiation," said Ajay Bhatnagar, M.D., resident, department of radiation oncology, University of Pittsburgh School of Medicine.

CyberKnife is a non-invasive robotic radiosurgical device that can remove tumors and other lesions without open surgery, using a robotic arm, controlled by a computer, that sends multiple beams of high-dose radiation directly to the tumor site.

Also involved in the study from the University of Pittsburgh were Peter Gerszten, M.D, department of neurological surgery; Anurag Agarwal, M.D., department of radiation oncology; C.W. Ozhasoglu, M.D., department of radiation oncology; William Vogel, R.T.T., department of radiation oncology; W.C. Welch, M.D., department of neurological surgery; and Shalom Kalnicki, M.D., now of the department of radiation oncology, Montefiore Medical Center, New York.

Clare Collins | EurekAlert!
Further information:
http://www.upmc.edu

More articles from Health and Medicine:

nachricht Oxygen can wake up dormant bacteria for antibiotic attacks
08.12.2016 | Penn State

nachricht NTU scientists build new ultrasound device using 3-D printing technology
07.12.2016 | Nanyang Technological University

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Significantly more productivity in USP lasers

In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.

Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...

Im Focus: Shape matters when light meets atom

Mapping the interaction of a single atom with a single photon may inform design of quantum devices

Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...

Im Focus: Novel silicon etching technique crafts 3-D gradient refractive index micro-optics

A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.

Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...

Im Focus: Quantum Particles Form Droplets

In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.

“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...

Im Focus: MADMAX: Max Planck Institute for Physics takes up axion research

The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.

The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ICTM Conference 2017: Production technology for turbomachine manufacturing of the future

16.11.2016 | Event News

Innovation Day Laser Technology – Laser Additive Manufacturing

01.11.2016 | Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

 
Latest News

Closing the carbon loop

08.12.2016 | Life Sciences

Applicability of dynamic facilitation theory to binary hard disk systems

08.12.2016 | Physics and Astronomy

Scientists track chemical and structural evolution of catalytic nanoparticles in 3-D

08.12.2016 | Materials Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>