Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Cyberknife radiosurgery is a safe and effective treatment for benign tumors

06.10.2004


Treating benign tumors outside the brain with CyberKnife Frameless Radiosurgery resulted in significant improvement in symptoms and minimal toxicity, according to a study by University of Pittsburgh School of Medicine researchers presented today at the 46th Annual Meeting of the American Society for Therapeutic Radiology and Oncology (ASTRO) in Atlanta.



"While stereotactic radiosurgery for the treatment of benign brain tumors has become widely accepted, our knowledge about the use of this technology for benign tumors outside the brain has been limited," said Steve Burton, M.D., study co-author and assistant professor, department of radiation oncology, University of Pittsburgh School of Medicine. "The results of our study indicate that treating these tumors with CyberKnife is safe and effective and can successfully control their growth and progression."

The study, whose purpose was to evaluate the feasibility, toxicity and local control of patients with symptomatic benign tumors treated with CyberKnife, evaluated 50 benign tumors in 35 patients who underwent radiosurgery between 2001 and 2004 at the University of Pittsburgh Medical Center. The tumors were located in the spine (36), neck (6), skull (3), eye (3) and brainstem (2). Seventy-eight percent of patients treated with CyberKnife experienced an improvement in their pre-treatment symptoms, which included pain and weakness. The local control rate – the rate at which the tumor’s growth was controlled locally – was 96 percent for the 26 patients who underwent follow-up imaging from one to 25 months after the treatment was administered.


"Our findings demonstrate that CyberKnife may offer a promising treatment option for patients with benign tumors who are not candidates for surgery or whose tumors are not amenable to surgery," said Dr. Burton. "The potential benefits are significant and include short-term treatment time in an outpatient setting with rapid recovery and symptomatic response." Dr. Burton added that follow-up studies will seek to assess the long-term tumor control rates as well as any future effects.

"This study represents the largest to date on the use of frameless radiosurgery to treat benign extra-cranial lesions, and the results thus far are very encouraging. Of noteworthy interest, CyberKnife was able to control aggressive benign tumors that had progressed despite surgery and/or conventional radiation," said Ajay Bhatnagar, M.D., resident, department of radiation oncology, University of Pittsburgh School of Medicine.

CyberKnife is a non-invasive robotic radiosurgical device that can remove tumors and other lesions without open surgery, using a robotic arm, controlled by a computer, that sends multiple beams of high-dose radiation directly to the tumor site.

Also involved in the study from the University of Pittsburgh were Peter Gerszten, M.D, department of neurological surgery; Anurag Agarwal, M.D., department of radiation oncology; C.W. Ozhasoglu, M.D., department of radiation oncology; William Vogel, R.T.T., department of radiation oncology; W.C. Welch, M.D., department of neurological surgery; and Shalom Kalnicki, M.D., now of the department of radiation oncology, Montefiore Medical Center, New York.

Clare Collins | EurekAlert!
Further information:
http://www.upmc.edu

More articles from Health and Medicine:

nachricht Tracking movement of immune cells identifies key first steps in inflammatory arthritis
23.01.2017 | Massachusetts General Hospital

nachricht Team discovers how bacteria exploit a chink in the body's armor
20.01.2017 | University of Illinois at Urbana-Champaign

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Quantum optical sensor for the first time tested in space – with a laser system from Berlin

For the first time ever, a cloud of ultra-cold atoms has been successfully created in space on board of a sounding rocket. The MAIUS mission demonstrates that quantum optical sensors can be operated even in harsh environments like space – a prerequi-site for finding answers to the most challenging questions of fundamental physics and an important innovation driver for everyday applications.

According to Albert Einstein's Equivalence Principle, all bodies are accelerated at the same rate by the Earth's gravity, regardless of their properties. This...

Im Focus: Traffic jam in empty space

New success for Konstanz physicists in studying the quantum vacuum

An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...

Im Focus: How gut bacteria can make us ill

HZI researchers decipher infection mechanisms of Yersinia and immune responses of the host

Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...

Im Focus: Interfacial Superconductivity: Magnetic and superconducting order revealed simultaneously

Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.

While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...

Im Focus: Studying fundamental particles in materials

Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales

Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Sustainable Water use in Agriculture in Eastern Europe and Central Asia

19.01.2017 | Event News

12V, 48V, high-voltage – trends in E/E automotive architecture

10.01.2017 | Event News

2nd Conference on Non-Textual Information on 10 and 11 May 2017 in Hannover

09.01.2017 | Event News

 
Latest News

Arctic melt ponds form when meltwater clogs ice pores

24.01.2017 | Earth Sciences

Synthetic nanoparticles achieve the complexity of protein molecules

24.01.2017 | Life Sciences

PPPL physicist uncovers clues to mechanism behind magnetic reconnection

24.01.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>