Treating benign tumors outside the brain with CyberKnife Frameless Radiosurgery resulted in significant improvement in symptoms and minimal toxicity, according to a study by University of Pittsburgh School of Medicine researchers presented today at the 46th Annual Meeting of the American Society for Therapeutic Radiology and Oncology (ASTRO) in Atlanta.
"While stereotactic radiosurgery for the treatment of benign brain tumors has become widely accepted, our knowledge about the use of this technology for benign tumors outside the brain has been limited," said Steve Burton, M.D., study co-author and assistant professor, department of radiation oncology, University of Pittsburgh School of Medicine. "The results of our study indicate that treating these tumors with CyberKnife is safe and effective and can successfully control their growth and progression."
The study, whose purpose was to evaluate the feasibility, toxicity and local control of patients with symptomatic benign tumors treated with CyberKnife, evaluated 50 benign tumors in 35 patients who underwent radiosurgery between 2001 and 2004 at the University of Pittsburgh Medical Center. The tumors were located in the spine (36), neck (6), skull (3), eye (3) and brainstem (2). Seventy-eight percent of patients treated with CyberKnife experienced an improvement in their pre-treatment symptoms, which included pain and weakness. The local control rate – the rate at which the tumors growth was controlled locally – was 96 percent for the 26 patients who underwent follow-up imaging from one to 25 months after the treatment was administered.
Clare Collins | EurekAlert!
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