A new non-invasive test for kidney disease, developed by clinicians at Hammersmith Hospitals NHS Trust and Imperial College London, is providing a simple, safe, cheap and reliable method of detecting kidney disease. The new test, reported today in the journal Nephrology Dialysis Transplantation, can detect disease before symptoms become apparent, and offers a quicker way of finding out if patients are responding to treatment – which could mean that some patients might not need costly dialysis.
Around 100,000 people in the UK have kidney disease, and the number is increasing, costing the NHS over £2 billion annually. Over 7000 people die from kidney failure every year. “Patients with a progressive kidney disease due to vasculitis* often develop kidney failure, the only treatment for which is dialysis or kidney transplant,” explains Dr Fred Tam, consultant nephrologist at Charing Cross and Hammersmith Hospitals and senior lecturer at Imperial College London. “By looking at a chemical produced when the kidney becomes inflamed, we can test patient’s urine for the level of disease, often before clinical symptoms appear.” The test could eventually replace the need to take biopsies from the kidney – a complicated and uncomfortable surgical procedure.
Current treatments for kidney vasculitis involve using drugs that knock out the body’s immune system. These drugs can cause side effects, including vulnerability to infection and risk of reduced fertility. This new test can accurately measure response to treatment, allowing clinicians to tailor treatments to individual patients. “The test can tell us if a treatment is working, and shows us, before it is too late, if we need to change the medication, without the need to perform a biopsy,” adds Dr Tam.
Simon Wilde | alfa
Organ-on-a-chip mimics heart's biomechanical properties
23.02.2017 | Vanderbilt University
Researchers identify cause of hereditary skeletal muscle disorder
22.02.2017 | Klinikum der Universität München
In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport
Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...
The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.
The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...
Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...
Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".
Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...
13.02.2017 | Event News
10.02.2017 | Event News
09.02.2017 | Event News
24.02.2017 | Life Sciences
24.02.2017 | Life Sciences
24.02.2017 | Trade Fair News