A tiny capsule containing tissue that secretes a cocktail of brain-nourishing neurotrophic factors may one day help reduce the damage and disability of stroke, according to research published in the September issue of Stroke.
Choroid plexus tissue has innate roles in developing and protecting the brain and when additional tissue is transplanted into an animal model of stroke, it reduces stroke size by about 65 percent, Medical College of Georgia researchers report. "What we have seen is the reduction of the size of the stroke in the brain, and the animals that received the transplant showed functional recovery in motor as well as neurological function," said Dr. Cesario V. Borlongan, MCG neuroscientist and first author on the paper.
The study is an important step in moving the potential treatment to clinical trials because the porcine choroid plexus tissue also could be used in humans, Dr. Borlongan said. The cells of the pig choroid plexus are similar in size and function to human cells and pig brain tissue has been used in humans to treat Parkinsons disease.
Toni Baker | EurekAlert!
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Staphylococcus aureus is a feared pathogen (MRSA, multi-resistant S. aureus) due to frequent resistances against many antibiotics, especially in hospital infections. Researchers at the Paul-Ehrlich-Institut have identified immunological processes that prevent a successful immune response directed against the pathogenic agent. The delivery of bacterial proteins with RNA adjuvant or messenger RNA (mRNA) into immune cells allows the re-direction of the immune response towards an active defense against S. aureus. This could be of significant importance for the development of an effective vaccine. PLOS Pathogens has published these research results online on 25 May 2017.
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Physicists from the University of Würzburg are capable of generating identical looking single light particles at the push of a button. Two new studies now demonstrate the potential this method holds.
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Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.
Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...
An Australian-Chinese research team has created the world's thinnest hologram, paving the way towards the integration of 3D holography into everyday...
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26.05.2017 | Life Sciences
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