Bone marrow derived stem cells can give rise to heart muscle cells. This plasticity concept – the ability of bone marrow cell to transdifferentiate into heart muscle cell – is supported by experimental and clinical data. Another possibility is to replace the missing function by causing transdifferentiation of existing cells. Transdifferentiation means converting one sort of cell, e.g. fibroblast, into another, e.g. muscle cell. There is real hope that we may be able to control this unique phenomenon to produce many heart cells to create a new heart muscle based on cells harvested from the patient himself.
These plasticity concepts have challenged the traditional dogma of tissue specific stem cell differentiation in adults and have raised hot debate. Many scientists have suggested alternative interpretations for plasticity research findings. Furthermore, recently, the debate regarding bone marrow and other adult stem cell plasticity has moved into the political and public zone. Opponents of human embryonic stem cell research see the plasticity of adult cells as a means of avoiding the use of human blastocysts (embryos a few days old) that is required to obtain pluripotent embryonic stem cells.
Despite the plasticity controversy and our limited understanding of stem cell plasticity, we hope that if we can control this process we may be able to use adult cells to produce new heart tissue for transplant and heart repair. J Leor (TEl Hashomer, IL)
Camilla Dormer | alfa
Organ-on-a-chip mimics heart's biomechanical properties
23.02.2017 | Vanderbilt University
Researchers identify cause of hereditary skeletal muscle disorder
22.02.2017 | Klinikum der Universität München
In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport
Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...
The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.
The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...
Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...
Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".
Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...
13.02.2017 | Event News
10.02.2017 | Event News
09.02.2017 | Event News
24.02.2017 | Life Sciences
24.02.2017 | Life Sciences
24.02.2017 | Trade Fair News