Bone marrow derived stem cells can give rise to heart muscle cells. This plasticity concept – the ability of bone marrow cell to transdifferentiate into heart muscle cell – is supported by experimental and clinical data. Another possibility is to replace the missing function by causing transdifferentiation of existing cells. Transdifferentiation means converting one sort of cell, e.g. fibroblast, into another, e.g. muscle cell. There is real hope that we may be able to control this unique phenomenon to produce many heart cells to create a new heart muscle based on cells harvested from the patient himself.
These plasticity concepts have challenged the traditional dogma of tissue specific stem cell differentiation in adults and have raised hot debate. Many scientists have suggested alternative interpretations for plasticity research findings. Furthermore, recently, the debate regarding bone marrow and other adult stem cell plasticity has moved into the political and public zone. Opponents of human embryonic stem cell research see the plasticity of adult cells as a means of avoiding the use of human blastocysts (embryos a few days old) that is required to obtain pluripotent embryonic stem cells.
Despite the plasticity controversy and our limited understanding of stem cell plasticity, we hope that if we can control this process we may be able to use adult cells to produce new heart tissue for transplant and heart repair. J Leor (TEl Hashomer, IL)
Camilla Dormer | alfa
Team discovers how bacteria exploit a chink in the body's armor
20.01.2017 | University of Illinois at Urbana-Champaign
Rabies viruses reveal wiring in transparent brains
19.01.2017 | Rheinische Friedrich-Wilhelms-Universität Bonn
An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...
Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...
Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.
While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...
Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales
Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...
Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.
As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...
19.01.2017 | Event News
10.01.2017 | Event News
09.01.2017 | Event News
20.01.2017 | Awards Funding
20.01.2017 | Materials Sciences
20.01.2017 | Life Sciences