The origins of rheumatoid arthritis (RA) have been studied with the help of data generated from close to 2000 patients with recent onset RA, who have been followed longitudinally be means of structured surveillance programs in Swedish Rheumatology and coordinated from the Karolinska Institutet and Karolinska University Hospital.
"One interesting finding is that smoking in the context of certain genetic predispositions, increases the risk for rheumatoid arthritis in a dramatic way, i.e. a marked gene-environment interaction is present between genes and environment in RA. The findings reinforce the special need for programs aimed at cessation of smoking in individuals with RA and at risk for RA" says Lars Klareskog, Professor at Karolinska Institutet.
The outcomes of RA, and in particular the results of different treatments have also been studied with the help of longitudinal structured surveillance programs. "Here, we have been able to monitor both effects and adverse effects of conventional as well as novel "biological" therapies against RA in clinical practice. The systems have enabled us to study the prognostic value of immunologic as well as genetic factors, and thereby helped in optimising therapy for the individual patient" says Lars Klareskog.
Pontus Bråmer | alfa
NIH scientists describe potential antibody treatment for multidrug-resistant K. pneumoniae
14.03.2018 | NIH/National Institute of Allergy and Infectious Diseases
Researchers identify key step in viral replication
13.03.2018 | University of Pittsburgh Schools of the Health Sciences
In just a few weeks from now, the Chinese space station Tiangong-1 will re-enter the Earth's atmosphere where it will to a large extent burn up. It is possible that some debris will reach the Earth's surface. Tiangong-1 is orbiting the Earth uncontrolled at a speed of approx. 29,000 km/h.Currently the prognosis relating to the time of impact currently lies within a window of several days. The scientists at Fraunhofer FHR have already been monitoring Tiangong-1 for a number of weeks with their TIRA system, one of the most powerful space observation radars in the world, with a view to supporting the German Space Situational Awareness Center and the ESA with their re-entry forecasts.
Following the loss of radio contact with Tiangong-1 in 2016 and due to the low orbital height, it is now inevitable that the Chinese space station will...
Fraunhofer Institute for Organic Electronics, Electron Beam and Plasma Technology FEP, provider of research and development services for OLED lighting solutions, announces the founding of the “OLED Licht Forum” and presents latest OLED design and lighting solutions during light+building, from March 18th – 23rd, 2018 in Frankfurt a.M./Germany, at booth no. F91 in Hall 4.0.
They are united in their passion for OLED (organic light emitting diodes) lighting with all of its unique facets and application possibilities. Thus experts in...
A new scenario seeking to explain how Mars' putative oceans came and went over the last 4 billion years implies that the oceans formed several hundred million...
For the first time, an interdisciplinary team from the University of Basel has succeeded in integrating artificial organelles into the cells of live zebrafish embryos. This innovative approach using artificial organelles as cellular implants offers new potential in treating a range of diseases, as the authors report in an article published in Nature Communications.
In the cells of higher organisms, organelles such as the nucleus or mitochondria perform a range of complex functions necessary for life. In the networks of...
Animal photoreceptors capture light with photopigments. Researchers from the University of Göttingen have now discovered that these photopigments fulfill an...
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