Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Red wine more heart-healthy than gin

16.08.2004


When the choice is red wine or gin, choose red wine – at least when considering your heart’s health.



That’s according to a recent study by Jefferson Medical College researchers, who compared the effects of drinking either red wine or gin on several biochemical markers in the blood. Red wine contains many complex compounds including polyphenols, which are absent from gin. They found that drinking red wine had a much greater effect in lowering levels in the bloodstream of so-called "anti-inflammatory" substances that are risk factors in the development of heart disease and stroke.

The results, which appeared recently in the journal Atherosclerosis, didn’t surprise co-author Emanuel Rubin, M.D., who led the study. "It’s clear from these results that while drinking some form of alcohol lowers inflammatory markers, red wine has a much greater effect than gin," says Dr. Rubin, Distinguished Professor of Pathology at Jefferson Medical College of Thomas Jefferson University in Philadelphia.


While there are well known associations between alcohol and a lowered risk of heart attack and stroke – the so-called "French paradox," for example – Dr. Rubin says that "breaking down the data epidemiologically" has been difficult.

To find evidence related to alcohol’s effect in reducing heart attack and stroke, he and his colleagues at the University of Barcelona turned to "surrogate" or substitute markers of disease. Inflammation, he notes, has long been implicated in the development of atherosclerosis and coronary artery disease. "High levels of c-reactive proteins and other markers of inflammation in the blood are risk factors that have been implicated in coronary artery disease and ischemic stroke," he says.

The Jefferson-led team compared the effects of red wine and gin on the levels of inflammatory biomarkers in the blood, including adhesion molecules, chemokines and white blood cells that are related to atherosclerosis. According to Dr. Rubin, no clinical trials have been done comparing the effect of red wine to that of alcoholic beverages with low levels of non-alcoholic substances, such as polyphenols.

In the first part of the study, the researcher gave 20 subjects in two groups two drinks a day of either wine or gin for 28 days. That was followed by a "washout period" of 15 days with no alcohol. In the second part of the trial, those who received red wine the first time then were given gin. Those who had gin first then received red wine. The researchers measured levels of biomarkers before and after each half of the trial. They attempted to rigorously control subjects’ diets.

Both wine and gin showed anti-inflammatory effects. Both groups had reduced levels of fibrinogen which clots blood but is not an inflammatory marker, and IL-1, which is. Raised levels of fibrinogen are a risk factor for heart attack.

But red wine also dramatically lowered the levels of inflammatory molecules such as adhesion molecules, and proteins in monocytes and lymphocytes.

Dr. Rubin argues that one or two glasses of red wine a day may be beneficial, and that there is some degree of protection from heart disease and stroke by alcoholic beverages in general. Still, the results are only indirect evidence and can’t prove a protective effect against the development of atherosclerosis. The study is far too brief to analyze a process that takes years to develop, he says. "It’s tough to root out just what is going on," he says. "There will have to be long-term epidemiological studies done."

Steve Benowitz | EurekAlert!
Further information:
http://www.jefferson.edu

More articles from Health and Medicine:

nachricht Penn study identifies new malaria parasites in wild bonobos
21.11.2017 | University of Pennsylvania School of Medicine

nachricht NIST scientists discover how to switch liver cancer cell growth from 2-D to 3-D structures
17.11.2017 | National Institute of Standards and Technology (NIST)

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Nanoparticles help with malaria diagnosis – new rapid test in development

The WHO reports an estimated 429,000 malaria deaths each year. The disease mostly affects tropical and subtropical regions and in particular the African continent. The Fraunhofer Institute for Silicate Research ISC teamed up with the Fraunhofer Institute for Molecular Biology and Applied Ecology IME and the Institute of Tropical Medicine at the University of Tübingen for a new test method to detect malaria parasites in blood. The idea of the research project “NanoFRET” is to develop a highly sensitive and reliable rapid diagnostic test so that patient treatment can begin as early as possible.

Malaria is caused by parasites transmitted by mosquito bite. The most dangerous form of malaria is malaria tropica. Left untreated, it is fatal in most cases....

Im Focus: A “cosmic snake” reveals the structure of remote galaxies

The formation of stars in distant galaxies is still largely unexplored. For the first time, astron-omers at the University of Geneva have now been able to closely observe a star system six billion light-years away. In doing so, they are confirming earlier simulations made by the University of Zurich. One special effect is made possible by the multiple reflections of images that run through the cosmos like a snake.

Today, astronomers have a pretty accurate idea of how stars were formed in the recent cosmic past. But do these laws also apply to older galaxies? For around a...

Im Focus: Visual intelligence is not the same as IQ

Just because someone is smart and well-motivated doesn't mean he or she can learn the visual skills needed to excel at tasks like matching fingerprints, interpreting medical X-rays, keeping track of aircraft on radar displays or forensic face matching.

That is the implication of a new study which shows for the first time that there is a broad range of differences in people's visual ability and that these...

Im Focus: Novel Nano-CT device creates high-resolution 3D-X-rays of tiny velvet worm legs

Computer Tomography (CT) is a standard procedure in hospitals, but so far, the technology has not been suitable for imaging extremely small objects. In PNAS, a team from the Technical University of Munich (TUM) describes a Nano-CT device that creates three-dimensional x-ray images at resolutions up to 100 nanometers. The first test application: Together with colleagues from the University of Kassel and Helmholtz-Zentrum Geesthacht the researchers analyzed the locomotory system of a velvet worm.

During a CT analysis, the object under investigation is x-rayed and a detector measures the respective amount of radiation absorbed from various angles....

Im Focus: Researchers Develop Data Bus for Quantum Computer

The quantum world is fragile; error correction codes are needed to protect the information stored in a quantum object from the deteriorating effects of noise. Quantum physicists in Innsbruck have developed a protocol to pass quantum information between differently encoded building blocks of a future quantum computer, such as processors and memories. Scientists may use this protocol in the future to build a data bus for quantum computers. The researchers have published their work in the journal Nature Communications.

Future quantum computers will be able to solve problems where conventional computers fail today. We are still far away from any large-scale implementation,...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Ecology Across Borders: International conference brings together 1,500 ecologists

15.11.2017 | Event News

Road into laboratory: Users discuss biaxial fatigue-testing for car and truck wheel

15.11.2017 | Event News

#Berlin5GWeek: The right network for Industry 4.0

30.10.2017 | Event News

 
Latest News

Previous evidence of water on mars now identified as grainflows

21.11.2017 | Physics and Astronomy

NASA's James Webb Space Telescope completes final cryogenic testing

21.11.2017 | Physics and Astronomy

New catalyst controls activation of a carbon-hydrogen bond

21.11.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>