Encouraging results of Phase II conformal radiation trial for ependymoma could resolve the dilemma on whether to withhold therapeutic radiation from children to preserve their cognitive development
A radiation therapy technique that kills brain tumors in children while sparing normal tissue allows young patients to enjoy normal development of memory, reasoning, problem-solving and other cognitive functions, according to investigators at St. Jude Children’s Research Hospital. The results of a Phase II clinical trial of this technique, called conformal radiation therapy (CRT), hold promise for sparing cognitive development even in children younger than three years.
This research is published in the August issue of the Journal of Clinical Oncology. The St. Jude study found that about 75 percent of the children treated for ependymoma with CRT did not experience progression of their cancer after three years, and their cognitive development was not significantly impaired by radiation therapy.
Bonnie Cameron | EurekAlert!
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