Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Food With The Guts To Stand Up To Cancer

22.07.2004


Cancers of the gut are one of the major causes of death from cancer, but a review published this week shows that they are also amongst the most preventable through changes in diet.



Of the 10 million new cases of cancer diagnosed in 2000, around 2.3 million were cancers of the digestive organs – pharynx, oesophagus, stomach or colorectum. Studies have shown that they are not purely genetic and can be modified by diet.

Professor Ian Johnson, author of the review and head of Gastrointestinal Health and Function at the Institute of Food Research, said: “The adverse effects of diet are caused by over-consumption of energy coupled with inadequate intakes of protective substances, such as micronutrients, dietary fibre and a variety of plant chemicals”.


The walls of the gut are lined with a layer of cells, the epithelium, covered with a film of mucus. The epithelium is the first contact for food, bacteria and anything else ingested. It is the body’s first line of internal defence, but can also be susceptible to the development of abnormalities over time. The epithelium is normally renewed by rapidly dividing stem cells, which can also give rise to new growths called polyps. These usually remain benign, but some may acquire so many genetic abnormalities that they eventually form a cancerous tumour.

There is evidence that some food components including fibre, folate, polyunsaturated fatty acids, plant chemicals such as glucosinolates or flavonoids and gut fermentation products such as butyrate can provide protection at various stages of cancer formation. For example, in research published in the same journal, enzymes called COX-2 that enable genetically abnormal cells to survive were suppressed by the flavonoid quercetin. Compounds can also increase the activity of detoxifying enzymes, and components in the diet have been shown to act synergistically in this way – so that they are even more effective when combined. These enzymes delete genetically damaged epithelial cells.

“Cancers of the colon and rectum are the most common cancers of the digestive organs worldwide”, said Professor Johnson. “But rates are much higher in developed countries. Colorectal cancer is clearly a disease of affluence and about 80 per cent of cases are attributable in some way to diet. Many of the mechanisms have yet to be discovered, but basically what this means is that people can help to protect themselves by controlling their weight and by eating diets rich in fruits and vegetables and other sources of fibre“.

“Cancer is a complex multistage process that can take a large proportion of a person’s lifespan to develop. Nutrition is potentially a powerful tool to interrupt many stages of that process, and could be much more effectively deployed by many people”, he said.

Zoe Dunford | alfa
Further information:
http://www.ifr.ac.uk

More articles from Health and Medicine:

nachricht NIST scientists discover how to switch liver cancer cell growth from 2-D to 3-D structures
17.11.2017 | National Institute of Standards and Technology (NIST)

nachricht High speed video recording precisely measures blood cell velocity
15.11.2017 | ITMO University

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: A “cosmic snake” reveals the structure of remote galaxies

The formation of stars in distant galaxies is still largely unexplored. For the first time, astron-omers at the University of Geneva have now been able to closely observe a star system six billion light-years away. In doing so, they are confirming earlier simulations made by the University of Zurich. One special effect is made possible by the multiple reflections of images that run through the cosmos like a snake.

Today, astronomers have a pretty accurate idea of how stars were formed in the recent cosmic past. But do these laws also apply to older galaxies? For around a...

Im Focus: Visual intelligence is not the same as IQ

Just because someone is smart and well-motivated doesn't mean he or she can learn the visual skills needed to excel at tasks like matching fingerprints, interpreting medical X-rays, keeping track of aircraft on radar displays or forensic face matching.

That is the implication of a new study which shows for the first time that there is a broad range of differences in people's visual ability and that these...

Im Focus: Novel Nano-CT device creates high-resolution 3D-X-rays of tiny velvet worm legs

Computer Tomography (CT) is a standard procedure in hospitals, but so far, the technology has not been suitable for imaging extremely small objects. In PNAS, a team from the Technical University of Munich (TUM) describes a Nano-CT device that creates three-dimensional x-ray images at resolutions up to 100 nanometers. The first test application: Together with colleagues from the University of Kassel and Helmholtz-Zentrum Geesthacht the researchers analyzed the locomotory system of a velvet worm.

During a CT analysis, the object under investigation is x-rayed and a detector measures the respective amount of radiation absorbed from various angles....

Im Focus: Researchers Develop Data Bus for Quantum Computer

The quantum world is fragile; error correction codes are needed to protect the information stored in a quantum object from the deteriorating effects of noise. Quantum physicists in Innsbruck have developed a protocol to pass quantum information between differently encoded building blocks of a future quantum computer, such as processors and memories. Scientists may use this protocol in the future to build a data bus for quantum computers. The researchers have published their work in the journal Nature Communications.

Future quantum computers will be able to solve problems where conventional computers fail today. We are still far away from any large-scale implementation,...

Im Focus: Wrinkles give heat a jolt in pillared graphene

Rice University researchers test 3-D carbon nanostructures' thermal transport abilities

Pillared graphene would transfer heat better if the theoretical material had a few asymmetric junctions that caused wrinkles, according to Rice University...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Ecology Across Borders: International conference brings together 1,500 ecologists

15.11.2017 | Event News

Road into laboratory: Users discuss biaxial fatigue-testing for car and truck wheel

15.11.2017 | Event News

#Berlin5GWeek: The right network for Industry 4.0

30.10.2017 | Event News

 
Latest News

NASA detects solar flare pulses at Sun and Earth

17.11.2017 | Physics and Astronomy

NIST scientists discover how to switch liver cancer cell growth from 2-D to 3-D structures

17.11.2017 | Health and Medicine

The importance of biodiversity in forests could increase due to climate change

17.11.2017 | Studies and Analyses

VideoLinks
B2B-VideoLinks
More VideoLinks >>>