Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Coronary Artery Bypass Surgery Not a Risk Factor for Dementia

22.07.2004


A study conducted by Mayo Clinic found that fears surrounding a connection between coronary artery bypass surgery (CABG) and dementia are unwarranted.

The link between CABG surgery and development of long-term cognitive decline has been controversial in medical literature.

“What we found is that in an observational study of residents of Rochester, Minn., CABG surgery was not a risk factor for dementia,” says David Knopman, M.D., Mayo Clinic neurologist and the study’s lead investigator. “It was reassuring that the surgery was not associated with increased risk of dementia.”



This study took a unique approach to this disputed topic. “In the literature on the long-term outcome of CABG surgery, most work focuses on those who have had the surgery, but there often isn’t a suitable comparison group,” says Dr. Knopman. His study started with dementia patients and worked backward to find out whether these patients were more likely to have previously undergone CABG surgery and compared them to the rate of CABG surgery in a non-demented control group.

Dr. Knopman explains that his patients often raise the issue of a dementia-heart surgery connection. “Patients often say, ‘My memory problems began after my heart surgery, even though I didn’t have any obvious complications of the surgery,’” he says.

Now, Dr. Knopman says he can respond that his study indicates that the heart surgery did not directly cause the memory issues. Memory problems may be due to complications experienced as a result of the CABG surgery, though, he says. However, if a patient had no complications due to the surgery, Dr. Knopman would look to other causes of the memory disorder rather than the bypass surgery.

The question, then, says Dr. Knopman, has been, “Could the CABG have a long-term consequence, even if the patients recovered without incident?

“It’s been thought that perhaps the bypass procedure itself, whether it caused acute confusion or not, could damage the brain and reduce the cerebral reserve for being able to tolerate future diseases,” says Dr. Knopman. “The arterial blood going from the heart to the brain is being manipulated in CABG surgery; it has the added potential for causing embolization from heart to head. Our findings do not support uncomplicated CABG surgery causing later dementia.”

Dr. Knopman indicates that his study does not discount the existence of short-term cognitive issues post-bypass surgery. “Our study doesn’t at all speak to short-term cognitive problems and CABG surgery — that wasn’t what we studied, and we can’t comment about that at all from this research,” he says.

The researchers used the Rochester Epidemiology Project medical records linkage system to identify dementia cases for 1990-1994. Dementia was defined by the criteria of the Diagnostic and Statistic Manual for Mental Disorders, Fourth Edition; postoperative confusion that later ceased was excluded. All dementia cases were then matched by age and sex to control cases that were dementia-free in the year of dementia onset in the dementia cases. In the five-year period studied, there were 564 dementia cases. Of these, 21 had undergone CABG before developing dementia. In the control group, 23 people had undergone CABG surgery.

| newswise
Further information:
http://www.mayo.edu

More articles from Health and Medicine:

nachricht 3D images of cancer cells in the body: Medical physicists from Halle present new method
16.05.2018 | Martin-Luther-Universität Halle-Wittenberg

nachricht Better equipped in the fight against lung cancer
16.05.2018 | Friedrich-Alexander-Universität Erlangen-Nürnberg

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: LZH showcases laser material processing of tomorrow at the LASYS 2018

At the LASYS 2018, from June 5th to 7th, the Laser Zentrum Hannover e.V. (LZH) will be showcasing processes for the laser material processing of tomorrow in hall 4 at stand 4E75. With blown bomb shells the LZH will present first results of a research project on civil security.

At this year's LASYS, the LZH will exhibit light-based processes such as cutting, welding, ablation and structuring as well as additive manufacturing for...

Im Focus: Self-illuminating pixels for a new display generation

There are videos on the internet that can make one marvel at technology. For example, a smartphone is casually bent around the arm or a thin-film display is rolled in all directions and with almost every diameter. From the user's point of view, this looks fantastic. From a professional point of view, however, the question arises: Is that already possible?

At Display Week 2018, scientists from the Fraunhofer Institute for Applied Polymer Research IAP will be demonstrating today’s technological possibilities and...

Im Focus: Explanation for puzzling quantum oscillations has been found

So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics

Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...

Im Focus: Dozens of binaries from Milky Way's globular clusters could be detectable by LISA

Next-generation gravitational wave detector in space will complement LIGO on Earth

The historic first detection of gravitational waves from colliding black holes far outside our galaxy opened a new window to understanding the universe. A...

Im Focus: Entangled atoms shine in unison

A team led by Austrian experimental physicist Rainer Blatt has succeeded in characterizing the quantum entanglement of two spatially separated atoms by observing their light emission. This fundamental demonstration could lead to the development of highly sensitive optical gradiometers for the precise measurement of the gravitational field or the earth's magnetic field.

The age of quantum technology has long been heralded. Decades of research into the quantum world have led to the development of methods that make it possible...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Save the date: Forum European Neuroscience – 07-11 July 2018 in Berlin, Germany

02.05.2018 | Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

Unique scope of UV LED technologies and applications presented in Berlin: ICULTA-2018

12.04.2018 | Event News

 
Latest News

NIST puts the optical microscope under the microscope to achieve atomic accuracy

23.05.2018 | Physics and Astronomy

Magnesium magnificent for plasmonic applications

23.05.2018 | Materials Sciences

Tunable diamond string may hold key to quantum memory

23.05.2018 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>