One of the strongest natural allies that cancer patients can tap to help fight tumor growth and metastasis may well be their own immune systems, and scientists affiliated with the Harvard University Medical School have devised ways of bolstering patients immune response against kidney and breast cancer.
In a paper published in the July 15 issue of the journal Clinical Cancer Research, the Harvard research team documented tumor regression in two breast cancer patients, and stabilization and containment of tumor growth in late stage breast and kidney patients through application of customized vaccinations made from the patients own tumor and immune system cells.
By fusing patients tumor cells with their immune system dendritic cells, researchers associated with the laboratory of Donald Kufe, M.D., professor of medicine at Dana-Farber Cancer Institute and Harvard Medical School, created customized antigen-presenting immune cells that train T cells to hunt, recognize and destroy the patients tumor cells.
Russell Vanderboom | EurekAlert!
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