Medical drug falsification mainly concerns those which are in high demand, such as antimalarials in African regions where malaria is endemic. IRD researchers (1) have examined the quality of antimalarial medicines available from informal distribution networks in Cameroon. They also assessed the impact of malaria patients’ taking these medicines, obtained on the illicit market, on their health. Self-medication is common but when it relies on supplies of poor-quality drugs it is ineffectual for controlling the disease. Quite the reverse, as it favours proliferation of treatment-resistant parasites leading to treatment failures and to people spending money futilely on health. Government measures for controlling such fraud are clearly necessary if public health is to be protected.
Large-scale diffusion and sale of medicines that do not comply with regulations or are poor in quality, especially in African countries, stems from several factors. These include: the intensification of trade, a growing demand for medical treatments or vaccines, a proliferation of small pharmaceutical industries, and inadequate regulation of manufacture and commerce of such products. Counterfeiting, which affects all classes of medical drugs, concerns mainly antibiotics and anti-parasitic drugs. This is the case of antimalarials, under high demand in African countries where malaria is endemic. This demand sustains the informal trade of false or poor quality antimalarial drugs, which is the final stage for distribution networks of counterfeit medicines that escape any control by health authorities.
To assess the effect this illegal sector has on malaria control, an IRD team investigated the origin and quality of several antimalarial drugs in tablet or capsule form. They were purported to contain chloroquine, quinine or a sulfadoxin-pyrimethamin mixture. These medicines were collected between 2001 and 2002 on the markets, from street vendors or patients who had obtained supplies from outside official networks, in several towns and villages in Cameroon.
Bénédicte Robert | EurekAlert!
Cholesterol-lowering drugs may fight infectious disease
22.08.2017 | Duke University
Once invincible superbug squashed by 'superteam' of antibiotics
22.08.2017 | University at Buffalo
Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.
As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...
Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.
Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...
For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.
While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...
An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.
The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...
A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.
Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...
16.08.2017 | Event News
04.08.2017 | Event News
26.07.2017 | Event News
23.08.2017 | Materials Sciences
23.08.2017 | Automotive Engineering
23.08.2017 | Life Sciences