Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Dietary Supplement with Plant Extract May Ease Hangover

29.06.2004


Individuals who took a dietary supplement containing extracts of Opuntia ficus indica, a type of prickly pear cactus, before consuming alcohol, had reduced symptoms of alcohol hangover compared to individuals who drank but took placebo, according to an article in the June 28 issue of The Archives of Internal Medicine, one of the JAMA/Archives journals.



Alcohol hangovers cause substantial economic and health consequences, the article states. The severity of alcohol hangovers may be related to inflammation caused by impurities in alcoholic beverages and byproducts of alcohol metabolism. C-reactive protein, a protein produced by the liver, becomes elevated after injury or trauma and is thought to be involved in inflammation and alcohol hangovers. An extract from the skin of the prickly pear fruit, Opuntia ficus indica (OFI) has been shown to reduce inflammation, the article states.

Jeff Wiese, M.D., of Tulane University, New Orleans, and colleagues investigated the effect of OFI on the symptoms of alcohol hangover.


The researchers randomly assigned 55 young adult volunteers (aged 21 to 35 years) to receive either OFI or placebo five hours before alcohol consumption. The study participants were given dinner (cheeseburger, fries and soda) four hours before alcohol consumption started, and were able to choose a single type of alcohol to drink for the study: vodka, gin, rum, bourbon, scotch, or tequila.

Over four hours of drinking, volunteers consumed up to 1.75 grams of alcohol per kilogram of body weight, a quantity that has produced hangovers in previous studies. One hour after alcohol consumption ended, the researchers measured blood alcohol levels, and the volunteers were driven home.

The next morning, volunteers returned to the study site and had their vital signs measured, and blood and urine samples were taken. Hangover severity (based on nine symptoms) and overall well-being were assessed on a scale (zero to six points, with six points indicating the worst well-being). Two weeks later, the study was repeated with the same volunteers except those that were previously given OFI were given placebo and vice versa.

The researchers found that three of the nine symptoms of hangover – nausea, dry mouth, and loss of appetite – were significantly reduced after taking OFI. The average score for well-being the next morning was 2.75 for volunteers who took OFI and 3.10 for volunteers who took placebo. The researchers also found that levels of C-reactive protein were strongly associated with hangover severity, and C-reactive protein levels were 40 percent higher in volunteers who took placebo compared with OFI.

“In this randomized, placebo-controlled, crossover trial, we found hangover symptom severity to be moderately reduced by an extract of the prickly pear plant, Opuntia ficus indica,” the authors write.

| newswise
Further information:
http://www.ama-assn.org

More articles from Health and Medicine:

nachricht Minimising risks of transplants
22.02.2018 | Friedrich-Alexander-Universität Erlangen-Nürnberg

nachricht FAU researchers demonstrate that an oxygen sensor in the body reduces inflammation
22.02.2018 | Friedrich-Alexander-Universität Erlangen-Nürnberg

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Developing reliable quantum computers

International research team makes important step on the path to solving certification problems

Quantum computers may one day solve algorithmic problems which even the biggest supercomputers today can’t manage. But how do you test a quantum computer to...

Im Focus: In best circles: First integrated circuit from self-assembled polymer

For the first time, a team of researchers at the Max-Planck Institute (MPI) for Polymer Research in Mainz, Germany, has succeeded in making an integrated circuit (IC) from just a monolayer of a semiconducting polymer via a bottom-up, self-assembly approach.

In the self-assembly process, the semiconducting polymer arranges itself into an ordered monolayer in a transistor. The transistors are binary switches used...

Im Focus: Demonstration of a single molecule piezoelectric effect

Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale

Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...

Im Focus: Hybrid optics bring color imaging using ultrathin metalenses into focus

For photographers and scientists, lenses are lifesavers. They reflect and refract light, making possible the imaging systems that drive discovery through the microscope and preserve history through cameras.

But today's glass-based lenses are bulky and resist miniaturization. Next-generation technologies, such as ultrathin cameras or tiny microscopes, require...

Im Focus: Stem cell divisions in the adult brain seen for the first time

Scientists from the University of Zurich have succeeded for the first time in tracking individual stem cells and their neuronal progeny over months within the intact adult brain. This study sheds light on how new neurons are produced throughout life.

The generation of new nerve cells was once thought to taper off at the end of embryonic development. However, recent research has shown that the adult brain...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

2nd International Conference on High Temperature Shape Memory Alloys (HTSMAs)

15.02.2018 | Event News

Aachen DC Grid Summit 2018

13.02.2018 | Event News

How Global Climate Policy Can Learn from the Energy Transition

12.02.2018 | Event News

 
Latest News

Decoding the structure of the huntingtin protein

22.02.2018 | Life Sciences

Camera technology in vehicles: Low-latency image data compression

22.02.2018 | Information Technology

Minimising risks of transplants

22.02.2018 | Health and Medicine

VideoLinks
Science & Research
Overview of more VideoLinks >>>