Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Method For Direct Treatment Of Intestinal Illnesses

29.06.2004


Wins Kaye Prize for Hebrew University PH.D. Student

A method for applying drugs directly to mucousal surfaces in the intestinal system has won a coveted prize for a graduate student at the Hebrew University of Jerusalem. The method has potential for providing better treatment for such diseases as ulcerative colitis and colon cancer.

The student is Tareq Jubeh, 30, of Jerusalem, who is working on his Ph.D. in the Department of Pharmaceutics at the Hebrew University School of Pharmacy under the supervision of Prof. Abraham Rubinstein and Prof. Yechezkel Barenholz.



Jubeh, married and the father of one child, was born in Jerusalem. He received his bachelor degree in pharmacy at the Applied Science University in Amman, Jordan, graduating first in his class in pharmaceutical sciences.

He received one of the Kaye Innovation Awards during the 67th meeting of the Hebrew University Board of Governors in June. The Kaye Awards have been given annually since 1993. Isaac Kaye of England, a prominent industrialist in the pharmaceutical industry, established the awards to encourage faculty, staff, and students of the Hebrew University to develop innovative methods and inventions with good commercial potential which will benefit the university and society.

The Kaye Award is the latest of a number of prizes won by Jubeh since coming to the Hebrew University School of Pharmacy in 1998, where he has earned a master’s degree and now serves as a teaching assistant. He previously won two awards for his work in teaching and supervision in pharmaceutics and industrial pharmacy courses, and earlier this year was awarded a prize for excellence in research carried out by Ph.D. students.

The technology developed by Jubeh is based on a novel liposomal delivery system which involves direct introduction via the rectum of a drug-containing liposomal suspension into the colon. Liposomes are microscopic or submicrosopic, sac-like membranic structures into which drugs can be encapsulated. These liposomal formulations have been shown to be effective in delivering drugs to the mucousal (interior) surfaces of the colon and small intestine.

A major element in this success was Jubeh’s discovery that the intestinal surface, which normally carries a negative electrical charge, changes to positive when there is an inflammation. Jubeh, therefore, designed liposomes that carry a counter (negative) charge, thereby creating electrostatic adhesion to the inflamed area and promoting healing. Further, he designed liposomal formulations with the ability to remain for predetermined, prolonged periods of times on the intestinal surfaces.

Jubeh is now planning to work towards perfecting an orally induced version of his drug-bearing liposomes in order to produce a non-invasive application.

Jerry Barach | Hebrew University
Further information:
http://www.huji.ac.il

More articles from Health and Medicine:

nachricht Speed data for the brain’s navigation system
06.12.2016 | Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)

nachricht Study suggests possible new target for treating and preventing Alzheimer's
02.12.2016 | Oregon Health & Science University

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Significantly more productivity in USP lasers

In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.

Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...

Im Focus: Shape matters when light meets atom

Mapping the interaction of a single atom with a single photon may inform design of quantum devices

Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...

Im Focus: Novel silicon etching technique crafts 3-D gradient refractive index micro-optics

A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.

Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...

Im Focus: Quantum Particles Form Droplets

In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.

“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...

Im Focus: MADMAX: Max Planck Institute for Physics takes up axion research

The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.

The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ICTM Conference 2017: Production technology for turbomachine manufacturing of the future

16.11.2016 | Event News

Innovation Day Laser Technology – Laser Additive Manufacturing

01.11.2016 | Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

 
Latest News

Robot on demand: Mobile machining of aircraft components with high precision

06.12.2016 | Power and Electrical Engineering

A new dead zone in the Indian Ocean could impact future marine nutrient balance

06.12.2016 | Earth Sciences

Significantly more productivity in USP lasers

06.12.2016 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>