Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Method For Direct Treatment Of Intestinal Illnesses

29.06.2004


Wins Kaye Prize for Hebrew University PH.D. Student

A method for applying drugs directly to mucousal surfaces in the intestinal system has won a coveted prize for a graduate student at the Hebrew University of Jerusalem. The method has potential for providing better treatment for such diseases as ulcerative colitis and colon cancer.

The student is Tareq Jubeh, 30, of Jerusalem, who is working on his Ph.D. in the Department of Pharmaceutics at the Hebrew University School of Pharmacy under the supervision of Prof. Abraham Rubinstein and Prof. Yechezkel Barenholz.



Jubeh, married and the father of one child, was born in Jerusalem. He received his bachelor degree in pharmacy at the Applied Science University in Amman, Jordan, graduating first in his class in pharmaceutical sciences.

He received one of the Kaye Innovation Awards during the 67th meeting of the Hebrew University Board of Governors in June. The Kaye Awards have been given annually since 1993. Isaac Kaye of England, a prominent industrialist in the pharmaceutical industry, established the awards to encourage faculty, staff, and students of the Hebrew University to develop innovative methods and inventions with good commercial potential which will benefit the university and society.

The Kaye Award is the latest of a number of prizes won by Jubeh since coming to the Hebrew University School of Pharmacy in 1998, where he has earned a master’s degree and now serves as a teaching assistant. He previously won two awards for his work in teaching and supervision in pharmaceutics and industrial pharmacy courses, and earlier this year was awarded a prize for excellence in research carried out by Ph.D. students.

The technology developed by Jubeh is based on a novel liposomal delivery system which involves direct introduction via the rectum of a drug-containing liposomal suspension into the colon. Liposomes are microscopic or submicrosopic, sac-like membranic structures into which drugs can be encapsulated. These liposomal formulations have been shown to be effective in delivering drugs to the mucousal (interior) surfaces of the colon and small intestine.

A major element in this success was Jubeh’s discovery that the intestinal surface, which normally carries a negative electrical charge, changes to positive when there is an inflammation. Jubeh, therefore, designed liposomes that carry a counter (negative) charge, thereby creating electrostatic adhesion to the inflamed area and promoting healing. Further, he designed liposomal formulations with the ability to remain for predetermined, prolonged periods of times on the intestinal surfaces.

Jubeh is now planning to work towards perfecting an orally induced version of his drug-bearing liposomes in order to produce a non-invasive application.

Jerry Barach | Hebrew University
Further information:
http://www.huji.ac.il

More articles from Health and Medicine:

nachricht Team discovers how bacteria exploit a chink in the body's armor
20.01.2017 | University of Illinois at Urbana-Champaign

nachricht Rabies viruses reveal wiring in transparent brains
19.01.2017 | Rheinische Friedrich-Wilhelms-Universität Bonn

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Traffic jam in empty space

New success for Konstanz physicists in studying the quantum vacuum

An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...

Im Focus: How gut bacteria can make us ill

HZI researchers decipher infection mechanisms of Yersinia and immune responses of the host

Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...

Im Focus: Interfacial Superconductivity: Magnetic and superconducting order revealed simultaneously

Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.

While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...

Im Focus: Studying fundamental particles in materials

Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales

Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...

Im Focus: Designing Architecture with Solar Building Envelopes

Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.

As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Sustainable Water use in Agriculture in Eastern Europe and Central Asia

19.01.2017 | Event News

12V, 48V, high-voltage – trends in E/E automotive architecture

10.01.2017 | Event News

2nd Conference on Non-Textual Information on 10 and 11 May 2017 in Hannover

09.01.2017 | Event News

 
Latest News

Helmholtz International Fellow Award for Sarah Amalia Teichmann

20.01.2017 | Awards Funding

An innovative high-performance material: biofibers made from green lacewing silk

20.01.2017 | Materials Sciences

Ion treatments for cardiac arrhythmia — Non-invasive alternative to catheter-based surgery

20.01.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>