Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

New Non-Invasive Method In Lung Diagnostics

24.06.2004


magnetic resonance imaging (MRI) as a non-invasive diagnostic method has been evolving into an attractive alternative to methods which are associated with radiation exposure. This development now also starts to manifest itself in lung perfusion imaging. This was reported by Dr. Christian Fink and colleagues of the Radiology Division of the Deutsches Krebsforschungszentrum (German Cancer Research Center) in a recent issue of the journal Radiology*.

Diagnosis of numerous diseases of the lungs requires precise imaging of lung perfusion. The standard method used is called perfusion scintigraphy. It involves injecting a radioactive substance into a patient’s bloodstream and then making a scan of its distribution in the lungs. An equally precise and absolutely radiation-free method for evaluating lung perfusion now turns out to be magnetic resonance imaging (MRI, also called nuclear magnetic resonance (NMR) scan).

In a comparative study of 7 healthy probands and 20 patients with suspected lung cancer, the researchers compared magnetic resonance imaging to the standard method of perfusion scintigraphy. MRI showed a higher temporal and spatial resolution in lung perfusion imaging and provides the additional advantage of three-dimensional image data, which makes it easier to recognize blood circulation changes. Perfusion defects caused by tumors were recognized with high accuracy. In direct comparison with the standard method, MRI was found to be at least equally good.



It is too early yet for MRI to become a routine clinical method of lung perfusion imaging. The value of the new method first needs to be assessed in larger studies. But the investigators are optimistic that the radiation-free option may turn into the method of choice: “Image resolution in MRI is about twice as high as in perfusion scintigraphy so that we expect a higher detail precision compared to the standard method”, says Fink. Alongside evaluation of perfusion, MRI also provides additional information, e.g. about the anatomy of blood vessels in the lungs and the temporal process of lung perfusion. Thus, it provides insight about both vessel organization and function of blood circulation down to the tiniest branches of the lungs.

The method can be used not only in diagnostics and surgery planning for lung tumor patients. It may in future also be beneficial in non-invasive diagnostics of other lung diseases such as pulmonary embolism, emphysema, and chronic bronchitis. Presently, however, MRI is substantially more expensive than the standard method (approx. 300 euros versus 75 euros per examination), since the remuneration system does not yet take adequate account of innovative methods of this kind.

The task of the Deutsches Krebsforschungszentrum in Heidelberg (German Cancer Research Center, DKFZ) is to systematically investigate the mechanisms of cancer development and to identify cancer risk factors. The results of this basic research are expected to lead to new approaches in the prevention, diagnosis, and treatment of cancer. The Center is financed to 90 percent by the Federal Ministry of Education and Research (BMBF) and to 10 percent by the State of Baden-Wuerttemberg. It is a member of the Helmholtz Association of National Research Centers (Helmholtz-Gemeinschaft Deutscher Forschungszentren e.V., HGF).

Julia Rautenstrauch | alfa
Further information:
http://www.dkfz.de

More articles from Health and Medicine:

nachricht Hot cars can hit deadly temperatures in as little as one hour
24.05.2018 | Arizona State University

nachricht 3D images of cancer cells in the body: Medical physicists from Halle present new method
16.05.2018 | Martin-Luther-Universität Halle-Wittenberg

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Powerful IT security for the car of the future – research alliance develops new approaches

The more electronics steer, accelerate and brake cars, the more important it is to protect them against cyber-attacks. That is why 15 partners from industry and academia will work together over the next three years on new approaches to IT security in self-driving cars. The joint project goes by the name Security For Connected, Autonomous Cars (SecForCARs) and has funding of €7.2 million from the German Federal Ministry of Education and Research. Infineon is leading the project.

Vehicles already offer diverse communication interfaces and more and more automated functions, such as distance and lane-keeping assist systems. At the same...

Im Focus: Molecular switch will facilitate the development of pioneering electro-optical devices

A research team led by physicists at the Technical University of Munich (TUM) has developed molecular nanoswitches that can be toggled between two structurally different states using an applied voltage. They can serve as the basis for a pioneering class of devices that could replace silicon-based components with organic molecules.

The development of new electronic technologies drives the incessant reduction of functional component sizes. In the context of an international collaborative...

Im Focus: LZH showcases laser material processing of tomorrow at the LASYS 2018

At the LASYS 2018, from June 5th to 7th, the Laser Zentrum Hannover e.V. (LZH) will be showcasing processes for the laser material processing of tomorrow in hall 4 at stand 4E75. With blown bomb shells the LZH will present first results of a research project on civil security.

At this year's LASYS, the LZH will exhibit light-based processes such as cutting, welding, ablation and structuring as well as additive manufacturing for...

Im Focus: Self-illuminating pixels for a new display generation

There are videos on the internet that can make one marvel at technology. For example, a smartphone is casually bent around the arm or a thin-film display is rolled in all directions and with almost every diameter. From the user's point of view, this looks fantastic. From a professional point of view, however, the question arises: Is that already possible?

At Display Week 2018, scientists from the Fraunhofer Institute for Applied Polymer Research IAP will be demonstrating today’s technological possibilities and...

Im Focus: Explanation for puzzling quantum oscillations has been found

So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics

Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

In focus: Climate adapted plants

25.05.2018 | Event News

Save the date: Forum European Neuroscience – 07-11 July 2018 in Berlin, Germany

02.05.2018 | Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

 
Latest News

In focus: Climate adapted plants

25.05.2018 | Event News

Flow probes from the 3D printer

25.05.2018 | Machine Engineering

Less is more? Gene switch for healthy aging found

25.05.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>