Periconceptional use of folic acid supplements is effective for the primary prevention of neural-tube defects and is recommended by reproductive health researchers
Recent research in this area, however, centres on two main debated questions. The first one is whether the use of folic acid alone or folic acid-containing multivitamins is better. The second one is whether high dose of folic acid (e.g. 5 mg) might be better than a daily multivitamin with low dose 0.4 - 0.8 mg of folic acid. This paper by Prof. Andrew E. Czeizel, receiver of 2002 award of US National Council on Folic Acid for Excellence in Research in the Field of Folic Acid and Birth Defects Prevention, presents a comparison of study of two intervention trials and a case-control surveillance of congenital abnormalities that involve very large population.
The first intervention trial is a randomized controlled trial involving 2,819 participants supplemented with multivitamins containing 0.8 mg of folic acid, and 2,683 unsupplemented participants. And the second intervention trial is a two-cohort controlled trial involving 3,069 participants supplemented with the same multivitamins, and 3,069 unsupplemented participants. The case-control surveillance of congenital abnormalities includes 30,054 pregnant women who received high dose (in general 6 mg) of folic acid supplementation - in a much larger racially homogeneous European-Caucasican population.
Anita Bay | alfa
Improving memory with magnets
28.03.2017 | McGill University
Graphene-based neural probes probe brain activity in high resolution
28.03.2017 | Graphene Flagship
The Institute of Semiconductor Technology and the Institute of Physical and Theoretical Chemistry, both members of the Laboratory for Emerging Nanometrology (LENA), at Technische Universität Braunschweig are partners in a new European research project entitled ChipScope, which aims to develop a completely new and extremely small optical microscope capable of observing the interior of living cells in real time. A consortium of 7 partners from 5 countries will tackle this issue with very ambitious objectives during a four-year research program.
To demonstrate the usefulness of this new scientific tool, at the end of the project the developed chip-sized microscope will be used to observe in real-time...
Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.
The results will be published on March 22 in the journal „Astronomy & Astrophysics“.
Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...
Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.
Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...
In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...
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28.03.2017 | Life Sciences
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28.03.2017 | Physics and Astronomy