With new technology that uses short strands of genetic material to shut down a specific gene, researchers have regulated immune system proteins to boost production of cells that seek and destroy cancer cells. This approach may improve the effectiveness of vaccines in the treatment of tumors, including malignant brain tumors.
Results of the study appear in the June issue of the European Journal of Immunology, and the research was conducted at Cedars-Sinais Maxine Dunitz Neurosurgical Institute, where clinical trials of dendritic cell immunotherapy have been underway for several years.
Dendritic cells are the immune systems most potent antigen-presenting cells – those that identify "foreign" substances for destruction. Because cancer cells often are not recognized by dendritic cells as antigens, the neurosurgeons and other scientists at the Institute have developed and studied a vaccine in the treatment of highly aggressive brain tumors called gliomas. They combine in the laboratory tumor cells that have been surgically removed and dendritic cells derived from a patients blood. The new cells are injected back into the patient to seek out other cancer cells for destruction.
Sandra Van | Van Communications
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Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.
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