Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Innovative ‘self healing’ bandage to help diabetics

25.05.2004


A revolutionary type of ‘self healing’ bandage that uses the patient’s own cells is being developed. The technique has already been tried successfully on patients with diabetic ulcers and in the long-term could offer a more effective, quicker and cost efficient way of treating many types of slow-healing wounds such as pressure ulcers. The bandages are already available for patients with severe burns.



The bandages have been developed by CellTran Ltd., a spin-out company from the University of Sheffield. CellTran has grown from fundamental research funded by the Engineering and Physical Sciences Research Council (EPSRC).

Levels of diabetes in the UK are forecast to rise significantly in the years ahead. Chronic ulcers affect many diabetics, with sufferers often attending clinics for months or years to have their wounds dressed. CellTran offers an innovative but simple approach to healing diabetic ulcers and other slow-healing wounds, based on a combination of surface engineering and cell biology.


A small tissue sample is taken from a patient and a culture is grown from the cells in a laboratory. The cells are then placed on a membrane made from a medical-grade polymer. The membrane has been treated with a special cell-friendly coating, enabling skin cells to attach and grow on this surface. When cells are ready, the cell-membrane bandage is taken to the relevant clinic and used to dress the patient’s wound instead of a standard bandage.

Because these cells belong to the patient, they are not rejected by the body but can actually transfer to the wound and grow. For particularly difficult wounds, the cells are applied every week. Early clinical studies have shown that weekly dressings enable these difficult wounds to heal in an average of eight weeks. Clinical trials are now under way, and the technique is also being used on other types of ulcer and on patients with extensive burns.

The underlying EPSRC-funded work at the University has focused on the development of surfaces that human cells will not only grow on but also transfer from to the patient’s wound. It is also developing new approaches to culturing human skin cells without using animal derived products such as bovine serum.

The new bandages could take some pressure off healthcare budgets by reducing the need for long-term patient treatment. CellTran also aims to develop off-the-shelf products which can be used in the patient’s home, avoiding visits to outpatient clinics altogether. Sheila MacNeil, CellTran’s Research & Development Director and Professor of Tissue Engineering at the University of Sheffield, says; “we are moving the technology through to clinical use as quickly as we can and our objective is to make it as simple to use and as low-cost as possible”.

Jane Reck | alfa
Further information:
http://www.epsrc.ac.uk

More articles from Health and Medicine:

nachricht Research offers clues for improved influenza vaccine design
09.04.2018 | NIH/National Institute of Allergy and Infectious Diseases

nachricht Injecting gene cocktail into mouse pancreas leads to humanlike tumors
06.04.2018 | University of Texas Health Science Center at San Antonio

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Writing and deleting magnets with lasers

Study published in the journal ACS Applied Materials & Interfaces is the outcome of an international effort that included teams from Dresden and Berlin in Germany, and the US.

Scientists at the Helmholtz-Zentrum Dresden-Rossendorf (HZDR) together with colleagues from the Helmholtz-Zentrum Berlin (HZB) and the University of Virginia...

Im Focus: Gamma-ray flashes from plasma filaments

Novel highly efficient and brilliant gamma-ray source: Based on model calculations, physicists of the Max PIanck Institute for Nuclear Physics in Heidelberg propose a novel method for an efficient high-brilliance gamma-ray source. A giant collimated gamma-ray pulse is generated from the interaction of a dense ultra-relativistic electron beam with a thin solid conductor. Energetic gamma-rays are copiously produced as the electron beam splits into filaments while propagating across the conductor. The resulting gamma-ray energy and flux enable novel experiments in nuclear and fundamental physics.

The typical wavelength of light interacting with an object of the microcosm scales with the size of this object. For atoms, this ranges from visible light to...

Im Focus: Basel researchers succeed in cultivating cartilage from stem cells

Stable joint cartilage can be produced from adult stem cells originating from bone marrow. This is made possible by inducing specific molecular processes occurring during embryonic cartilage formation, as researchers from the University and University Hospital of Basel report in the scientific journal PNAS.

Certain mesenchymal stem/stromal cells from the bone marrow of adults are considered extremely promising for skeletal tissue regeneration. These adult stem...

Im Focus: Like a wedge in a hinge

Researchers lay groundwork to tailor drugs for new targets in cancer therapy

In the fight against cancer, scientists are developing new drugs to hit tumor cells at so far unused weak points. Such a “sore spot” is the protein complex...

Im Focus: The Future of Ultrafast Solid-State Physics

In an article that appears in the journal “Review of Modern Physics”, researchers at the Laboratory for Attosecond Physics (LAP) assess the current state of the field of ultrafast physics and consider its implications for future technologies.

Physicists can now control light in both time and space with hitherto unimagined precision. This is particularly true for the ability to generate ultrashort...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

Unique scope of UV LED technologies and applications presented in Berlin: ICULTA-2018

12.04.2018 | Event News

IWOLIA: A conference bringing together German Industrie 4.0 and French Industrie du Futur

09.04.2018 | Event News

 
Latest News

Diamond-like carbon is formed differently to what was believed -- machine learning enables development of new model

19.04.2018 | Materials Sciences

Electromagnetic wizardry: Wireless power transfer enhanced by backward signal

19.04.2018 | Physics and Astronomy

Ultrafast electron oscillation and dephasing monitored by attosecond light source

19.04.2018 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>