Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

MR Spectroscopy Aids in Distinguishing Recurring Brain Tumors from Similar-Appearing Changes Related to Treatment

03.05.2004


MR spectroscopy may be a useful adjunct to conventional imaging to distinguish recurrent tumor from treatment-related change in the brain such as inflammation or dead cells, says a new study by researchers from the University of Michigan Medical Center in Ann Arbor, MI.



In the study, MR spectroscopy was performed on 27 patients who were previously treated with surgery, chemotherapy and radiation therapy for brain tumor. Results of the study revealed that Choline, Creatine and N-acetylaspartate, specific molecules used as markers for identification of tumors and which can be detected with MR spectroscopy, were all readily quantifiable in each patient, allowing accurate recognition. “MR spectroscopy is a tool that can provide a biochemical thumbprint or profile of the brain, allowing accurate identification of recurrent tumor from benign changes related to chemotherapy or radiation therapy,” said Patrick N. Weybright, MD, lead author of the study.

According to Dr. Weybright, a down side to MR spectroscopy is that it is usually more susceptible to artifacts from nearby bone and fluid, which can make it impossible to identify the molecules. However, he said, by using techniques to suppress the overwhelming signal from water, they were able to achieve multivoxel spectroscopy in 25 of 27 patients with no significant artifacts.


According to the authors, the role MR spectroscopy can play in distinguishing recurrent tumor from tumor-related change is an important one for the patient. “It affects patient lifestyle. Early identification of recurrent tumor can allow earlier implementation of treatment to stop the tumor recurrence, and identification of benign changes related to treatment can prevent unnecessary therapy,” said Dr. Weybright.

Dr. Weybright will present the study on May 3 during the American Roentgen Ray Society Annual Meeting in Miami Beach, FL.

Jason Ocker | ARRS
Further information:
http://www.arrs.org/scriptcontent/pressroom/archive/2004/r040503h.cfm

More articles from Health and Medicine:

nachricht Researchers identify new way to unmask melanoma cells to the immune system
17.01.2018 | Duke University Medical Center

nachricht Study advances gene therapy for glaucoma
17.01.2018 | University of Wisconsin-Madison

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Scientists decipher key principle behind reaction of metalloenzymes

So-called pre-distorted states accelerate photochemical reactions too

What enables electrons to be transferred swiftly, for example during photosynthesis? An interdisciplinary team of researchers has worked out the details of how...

Im Focus: The first precise measurement of a single molecule's effective charge

For the first time, scientists have precisely measured the effective electrical charge of a single molecule in solution. This fundamental insight of an SNSF Professor could also pave the way for future medical diagnostics.

Electrical charge is one of the key properties that allows molecules to interact. Life itself depends on this phenomenon: many biological processes involve...

Im Focus: Paradigm shift in Paris: Encouraging an holistic view of laser machining

At the JEC World Composite Show in Paris in March 2018, the Fraunhofer Institute for Laser Technology ILT will be focusing on the latest trends and innovations in laser machining of composites. Among other things, researchers at the booth shared with the Aachen Center for Integrative Lightweight Production (AZL) will demonstrate how lasers can be used for joining, structuring, cutting and drilling composite materials.

No other industry has attracted as much public attention to composite materials as the automotive industry, which along with the aerospace industry is a driver...

Im Focus: Room-temperature multiferroic thin films and their properties

Scientists at Tokyo Institute of Technology (Tokyo Tech) and Tohoku University have developed high-quality GFO epitaxial films and systematically investigated their ferroelectric and ferromagnetic properties. They also demonstrated the room-temperature magnetocapacitance effects of these GFO thin films.

Multiferroic materials show magnetically driven ferroelectricity. They are attracting increasing attention because of their fascinating properties such as...

Im Focus: A thermometer for the oceans

Measurement of noble gases in Antarctic ice cores

The oceans are the largest global heat reservoir. As a result of man-made global warming, the temperature in the global climate system increases; around 90% of...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

10th International Symposium: “Advanced Battery Power – Kraftwerk Batterie” Münster, 10-11 April 2018

08.01.2018 | Event News

See, understand and experience the work of the future

11.12.2017 | Event News

Innovative strategies to tackle parasitic worms

08.12.2017 | Event News

 
Latest News

Gran Chaco: Biodiversity at High Risk

17.01.2018 | Ecology, The Environment and Conservation

Only an atom thick: Physicists succeed in measuring mechanical properties of 2D monolayer materials

17.01.2018 | Physics and Astronomy

Fraunhofer HHI receives AIS Technology Innovation Award 2018 for 3D Human Body Reconstruction

17.01.2018 | Awards Funding

VideoLinks
B2B-VideoLinks
More VideoLinks >>>