MR spectroscopy may be a useful adjunct to conventional imaging to distinguish recurrent tumor from treatment-related change in the brain such as inflammation or dead cells, says a new study by researchers from the University of Michigan Medical Center in Ann Arbor, MI.
In the study, MR spectroscopy was performed on 27 patients who were previously treated with surgery, chemotherapy and radiation therapy for brain tumor. Results of the study revealed that Choline, Creatine and N-acetylaspartate, specific molecules used as markers for identification of tumors and which can be detected with MR spectroscopy, were all readily quantifiable in each patient, allowing accurate recognition. “MR spectroscopy is a tool that can provide a biochemical thumbprint or profile of the brain, allowing accurate identification of recurrent tumor from benign changes related to chemotherapy or radiation therapy,” said Patrick N. Weybright, MD, lead author of the study.
According to Dr. Weybright, a down side to MR spectroscopy is that it is usually more susceptible to artifacts from nearby bone and fluid, which can make it impossible to identify the molecules. However, he said, by using techniques to suppress the overwhelming signal from water, they were able to achieve multivoxel spectroscopy in 25 of 27 patients with no significant artifacts.
Jason Ocker | ARRS
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The WHO reports an estimated 429,000 malaria deaths each year. The disease mostly affects tropical and subtropical regions and in particular the African continent. The Fraunhofer Institute for Silicate Research ISC teamed up with the Fraunhofer Institute for Molecular Biology and Applied Ecology IME and the Institute of Tropical Medicine at the University of Tübingen for a new test method to detect malaria parasites in blood. The idea of the research project “NanoFRET” is to develop a highly sensitive and reliable rapid diagnostic test so that patient treatment can begin as early as possible.
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The formation of stars in distant galaxies is still largely unexplored. For the first time, astron-omers at the University of Geneva have now been able to closely observe a star system six billion light-years away. In doing so, they are confirming earlier simulations made by the University of Zurich. One special effect is made possible by the multiple reflections of images that run through the cosmos like a snake.
Today, astronomers have a pretty accurate idea of how stars were formed in the recent cosmic past. But do these laws also apply to older galaxies? For around a...
Just because someone is smart and well-motivated doesn't mean he or she can learn the visual skills needed to excel at tasks like matching fingerprints, interpreting medical X-rays, keeping track of aircraft on radar displays or forensic face matching.
That is the implication of a new study which shows for the first time that there is a broad range of differences in people's visual ability and that these...
Computer Tomography (CT) is a standard procedure in hospitals, but so far, the technology has not been suitable for imaging extremely small objects. In PNAS, a team from the Technical University of Munich (TUM) describes a Nano-CT device that creates three-dimensional x-ray images at resolutions up to 100 nanometers. The first test application: Together with colleagues from the University of Kassel and Helmholtz-Zentrum Geesthacht the researchers analyzed the locomotory system of a velvet worm.
During a CT analysis, the object under investigation is x-rayed and a detector measures the respective amount of radiation absorbed from various angles....
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