According to research work at the University Hospital, cell therapy could improve many of the motor deficits of patients with Parkinson’s Disease.
With Parkinson’s a degeneration of cell groups takes place and so, from a conceptual perspective, the perfect treatment would be to replace the cells lost. The big drawback in the search for a suitable cell is to find one that survives for a lengthy period within the brain, that integrates well into the brain structures in order to comply with a series of functions and one that is not rejected by the organism of the patient.
At the University Hospital a line of investigation is being carried out that is based on experimenting with stem cells having the ability to transform themselves into neurones and incorporate themselves into the brain. Two types of cells are currently being tested: one type consists of adult bone marrow stem cells. The aim is to obtain dopaminergic neurones from adult bone marrow stem cells. The next step will be to test to see if these neurones are able, once implanted in the brain, to ameliorate Parkinsonian symptoms in animals.
Garazi Andonegi | Basque research
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