Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Minimally invasive breast cancer treatment shows promise

30.03.2004


A pilot study using radiofrequency (RF) ablation to treat small breast cancers has found the procedure feasible and safe, according to an article appearing in the April issue of the journal Radiology.



"This study has added another potential weapon to the breast cancer treatment arsenal," said the study’s lead author, Bruno D. Fornage, M.D., who is a professor of radiology and surgical oncology at The University of Texas M. D. Anderson Cancer Center in Houston.

RF ablation treats tumors with heat produced by an electrical current. Ultrasound imaging is used to guide a needle-electrode to the tumor’s center, where a temperature of approximately 200º F is applied for 15 minutes to destroy malignant tissue.


To determine the feasibility and safety of RF ablation in the treatment of small breast cancers (2 centimeters or less in diameter--about the size of a grape), the researchers performed RF ablation on 21 breast cancers in 20 patients immediately before the patients underwent surgical lumpectomy (removal of the breast tumor and a small amount of surrounding tissue) or mastectomy (removal of the breast). After surgical excision, the specimens were evaluated by a pathologist to confirm whether RF ablation had eliminated all cancerous cells.

In all 21 cases, the target tumor that was seen on ultrasound was completely ablated with no adverse effects. In one of two patients who had received preoperative chemotherapy to shrink the tumor, residual microscopic cancer that did not show up on imaging was found around the ablated target.

Although the results of the feasibility and safety study were positive, this minimally invasive procedure is currently limited as a treatment because surrounding tissue is not removed from the tumor site with ablation. Therefore, physicians cannot test the tissue to be certain all cancer has been destroyed.

"This is an experimental study, and additional long-term trials will be needed before RF ablation becomes available as an alternative to surgery in the treatment for early breast cancer," Dr. Fornage said.


Radiology is a monthly scientific journal devoted to clinical radiology and allied sciences. The journal is edited by Anthony V. Proto, M.D., School of Medicine, Virginia Commonwealth University, Richmond, Virginia. Radiology is owned and published by the Radiological Society of North America, Inc. (http://radiology.rsnajnls.org)

The Radiological Society of North America is an association of more than 35,000 radiologists, radiation oncologists and related scientists committed to promoting excellence in radiology through education and by fostering research, with the ultimate goal of improving patient care. The Society is based in Oak Brook, Ill. (http://www.rsna.org)

"Small (2-cm) Breast Cancer Treated with US-guided Radiofrequency Ablation: Feasibility Study." Collaborating with Dr. Fornage on this study were Nour Sneige, M.D., Merrick I. Ross, M.D., Attiqa N. Mirza, M.D., Henry M. Kuerer, M.D., Ph.D., Beth S. Edeiken, M.D., Frederick C. Ames, M.D., Lisa A. Newman, M.D., Gildy V. Babiera, M.D., and S. Eva Singletary, M.D.

Maureen Morley | EurekAlert!
Further information:
http://radiology.rsnajnls.org
http://www.rsna.org

More articles from Health and Medicine:

nachricht Study suggests possible new target for treating and preventing Alzheimer's
02.12.2016 | Oregon Health & Science University

nachricht The first analysis of Ewing's sarcoma methyloma opens doors to new treatments
01.12.2016 | IDIBELL-Bellvitge Biomedical Research Institute

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Shape matters when light meets atom

Mapping the interaction of a single atom with a single photon may inform design of quantum devices

Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...

Im Focus: Novel silicon etching technique crafts 3-D gradient refractive index micro-optics

A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.

Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...

Im Focus: Quantum Particles Form Droplets

In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.

“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...

Im Focus: MADMAX: Max Planck Institute for Physics takes up axion research

The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.

The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...

Im Focus: Molecules change shape when wet

Broadband rotational spectroscopy unravels structural reshaping of isolated molecules in the gas phase to accommodate water

In two recent publications in the Journal of Chemical Physics and in the Journal of Physical Chemistry Letters, researchers around Melanie Schnell from the Max...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ICTM Conference 2017: Production technology for turbomachine manufacturing of the future

16.11.2016 | Event News

Innovation Day Laser Technology – Laser Additive Manufacturing

01.11.2016 | Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

 
Latest News

NASA's AIM observes early noctilucent ice clouds over Antarctica

05.12.2016 | Earth Sciences

Shape matters when light meets atom

05.12.2016 | Physics and Astronomy

Researchers uncover protein-based “cancer signature”

05.12.2016 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>