Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Jefferson-Led Study Shows Needle-Free Transdermal System as Effective as IV Pain Pump for Post-Surgical Pain While Giving Patien

17.03.2004


A needle-free, self-contained fentanyl patient-controlled transdermal system (PCTS) is as effective for post-surgical pain management as the traditional intravenous pump (IV), while giving patients more mobility and freeing nurses to devote more time to patient care. The study led by researchers from Jefferson Medical College of Thomas Jefferson University, Philadelphia, appears in the March 17 issue of the Journal of the American Medical Association (JAMA).

The multi-center study conducted at more than 30 sites nationwide demonstrated that a button-activated, fentanyl system that delivers pain medication through the skin could eliminate the need for IVs for post-surgical pain relief. The study was led by Eugene Viscusi, M.D., director of the Acute Pain Management Service at Thomas Jefferson University Hospital, Philadelphia. The fentanyl transdermal system would also offer the advantage of a needle-free, pre-programmed medication system in a small, self-contained unit.

“This is a miracle of miniaturization,” said Dr. Viscusi, assistant professor of Anesthesiology, Jefferson Medical College of Thomas Jefferson University.



The system, known as E-TRANS fentanyl PCTS, is approximately the size of a credit card, self adherent to the skin, pre-programmed and needle free. It delivers pain medication across the skin with a low level electric current when activated by the patient with a small button on the surface of the device.

The fentanyl transdermal system could be used for patients with moderate to severe post-operative pain after most surgeries including joint replacement, prostate surgery or gynecological procedures, the Jefferson anesthesiologist said.

“Anyone who has ever had surgery remembers the discomfort of having IVs and needles,” Dr. Viscusi said. “This patch system has a huge potential advantage.”

The PCTS, placed on an inpatient’s upper arm or chest by adhesive on the back of the patch, transmits the pain medication through the skin at the push of a button, explained Dr. Viscusi. When the patient pushes the button for pain, PCTS delivers medication over 10 minutes. The system has a “lock out” feature so a patient cannot administer more pain medication than is prescribed for him. The system is replaced every 24 hours as needed.

Without any tubing or equipment to encumber a patient’s movement, the patient can freely move about to perform needed physical therapy, Dr. Viscusi said.

The PCTS could also be a boon to nurses as nursing staff would not have to spend time setting up an IV and the time consuming standard pain pump currently used. This could allow nurses to devote more time to patient care instead of technology, he said.

The fentanyl patch system studied is currently under review by the U.S. Food and Drug Administration (FDA) and was developed by Ortho-McNeil Pharmaceuticals, Inc. and the ALZA Corporation, both subsidiaries of Johnson and Johnson.

Jeffrey Baxt | TJUH
Further information:
http://www.jeffersonhospital.org/news/e3front.dll?durki=17592

More articles from Health and Medicine:

nachricht Biofilm discovery suggests new way to prevent dangerous infections
23.05.2017 | University of Texas at Austin

nachricht Another reason to exercise: Burning bone fat -- a key to better bone health
19.05.2017 | University of North Carolina Health Care

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Strathclyde-led research develops world's highest gain high-power laser amplifier

The world's highest gain high power laser amplifier - by many orders of magnitude - has been developed in research led at the University of Strathclyde.

The researchers demonstrated the feasibility of using plasma to amplify short laser pulses of picojoule-level energy up to 100 millijoules, which is a 'gain'...

Im Focus: Can the immune system be boosted against Staphylococcus aureus by delivery of messenger RNA?

Staphylococcus aureus is a feared pathogen (MRSA, multi-resistant S. aureus) due to frequent resistances against many antibiotics, especially in hospital infections. Researchers at the Paul-Ehrlich-Institut have identified immunological processes that prevent a successful immune response directed against the pathogenic agent. The delivery of bacterial proteins with RNA adjuvant or messenger RNA (mRNA) into immune cells allows the re-direction of the immune response towards an active defense against S. aureus. This could be of significant importance for the development of an effective vaccine. PLOS Pathogens has published these research results online on 25 May 2017.

Staphylococcus aureus (S. aureus) is a bacterium that colonizes by far more than half of the skin and the mucosa of adults, usually without causing infections....

Im Focus: A quantum walk of photons

Physicists from the University of Würzburg are capable of generating identical looking single light particles at the push of a button. Two new studies now demonstrate the potential this method holds.

The quantum computer has fuelled the imagination of scientists for decades: It is based on fundamentally different phenomena than a conventional computer....

Im Focus: Turmoil in sluggish electrons’ existence

An international team of physicists has monitored the scattering behaviour of electrons in a non-conducting material in real-time. Their insights could be beneficial for radiotherapy.

We can refer to electrons in non-conducting materials as ‘sluggish’. Typically, they remain fixed in a location, deep inside an atomic composite. It is hence...

Im Focus: Wafer-thin Magnetic Materials Developed for Future Quantum Technologies

Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.

Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Marine Conservation: IASS Contributes to UN Ocean Conference in New York on 5-9 June

24.05.2017 | Event News

AWK Aachen Machine Tool Colloquium 2017: Internet of Production for Agile Enterprises

23.05.2017 | Event News

Dortmund MST Conference presents Individualized Healthcare Solutions with micro and nanotechnology

22.05.2017 | Event News

 
Latest News

New insights into the ancestors of all complex life

29.05.2017 | Earth Sciences

New photocatalyst speeds up the conversion of carbon dioxide into chemical resources

29.05.2017 | Life Sciences

NASA's SDO sees partial eclipse in space

29.05.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>