The University of California, Santa Barbara announced today that it has donated all rights to a patent that covers the novel use of an established class of cardiovascular medicines as a potential new drug against a global parasitic disease. The Institute for OneWorld Health, a nonprofit pharmaceutical company based in San Francisco, will use the UCSB discovery and the wealth of data associated with the medicines to accelerate drug development for treatment of schistosomiasis.
Two UCSB researchers discovered that calcium channel blockers may prove to be an inexpensive alternative for controlling schistosome infection, a serious global health problem that afflicts more than 200 million people annually in developing nations. An estimated 200,000 people, many of them older children, die every year from schistosomiasis. Many more suffer chronic damage to vital organs, including the liver and bladder.
The inventors are Mark Walter, a research biologist, and Armand Kuris, professor of biology. "Calcium channel blockers look very promising for the treatment of schistosomiasis, which is a devastating disease," said Kuris, an expert in parasitology and associate provost of the College of Creative Studies. Physicians routinely prescribe calcium channel blockers to treat high blood pressure, correct abnormal heart rhythms, treat panic attacks and bipolar disorder, and prevent migraine headaches.
Laser activated gold pyramids could deliver drugs, DNA into cells without harm
24.03.2017 | Harvard John A. Paulson School of Engineering and Applied Sciences
What does congenital Zika syndrome look like?
24.03.2017 | University of California - San Diego
Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.
The results will be published on March 22 in the journal „Astronomy & Astrophysics“.
Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...
Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.
Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...
In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...
20.03.2017 | Event News
14.03.2017 | Event News
07.03.2017 | Event News
24.03.2017 | Materials Sciences
24.03.2017 | Physics and Astronomy
24.03.2017 | Physics and Astronomy