Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Antibiotics may not be necessary when treating children with a simple skin abscess

24.02.2004


Physicians may not need to prescribe antibiotics when treating a common skin infection in children, according to researchers at UT Southwestern Medical Center at Dallas.


Research by (from left) Drs. Ana Maria Rios, R. Doug Hardy and Michael C. Lee has shown that antibiotics may not always be necessary when treating some common skin infections in children.



The findings, which appear in the February issue of The Pediatric Infectious Disease Journal, show draining a skin or soft-tissue abscess – a pus-filled boil – and packing the wound with gauze is adequate therapy for simple skin abscesses. Patients still need to seek medical attention for these boils even though they may not need antibiotics.

This traditional treatment is even effective when the antibiotic-resistant, methicillin-resistant Staphylococcus aureus (MRSA) causes the abscess. Children can get these boils from a scratch or prick, even when there are no known signs of a preceding trauma.


Antibiotic-resistant bacteria are often thought to be more virulent than their ancestors, said Dr. R. Doug Hardy, assistant professor of internal medicine and pediatrics and the study’s senior author. Many physicians now have questions regarding how aggressively to treat these antibiotic-resistant bacteria.

"We were surprised. What we found is that if a physician adequately drains the abscess, it will most likely get better with or without effective antibiotics," Dr. Hardy said.

At the beginning of the study, researchers were simply looking for alternative drugs and treatments for the methicillin-resistant Staphylococcus aureus. Abscesses caused by these bacteria have become extremely common in children.

"I think it’s good news for physicians. It addresses the dilemma of how to treat these kids," said Dr. Michael C. Lee, assistant professor of pediatrics and co-lead author of the study. "We needed a plan, and we needed to know how to deal with it better on a day-to-day basis."

The study is among the first to look at managing an infection caused by antibiotic-resistant bacteria, researchers said. Previous research has focused mainly on identifying antibiotic-resistant bacteria and determining frequency and risk of infections.

The prospective study, one of the largest to date on this subject, included 69 children. Patients’ average age was 5½ years. All children had their abscesses drained through incision, manually or spontaneously. Nearly all were initially treated with ineffective antibiotics before physicians knew whether patients were infected with the resistant bacteria.

In 21 children, the prescribed antibiotics were changed on their first follow-up visit to drugs that could kill the resistant bacteria, while in 37 children antibiotics were not adjusted. On further follow-up, researchers found no statistically significant differences with regard to fever or wound tenderness, discharge or size in patients whose antibiotic therapy was changed compared to those whose therapy was not changed to an effective antibiotic.

Four patients were hospitalized on the initial follow-up visit because the abscess had either increased or had not improved as physicians expected. One third of the patients with an abscess and cellulitis more than 5 centimeters in diameter were hospitalized. Ineffective antibiotic use from the initial visit did not predict whether a child would need to be hospitalized, according to the study. It is not known if these findings apply to infants.


###
Other UT Southwestern researchers involved in the study were Dr. Ana Rios (co-lead author on the study), Dr. Monica Fonseca-Aten and Dr. Asuncion Mejias, all postdoctoral trainee clinicians in pediatric infectious diseases; Dr. Dominick Cavuoti, assistant professor of pathology; and Dr. George McCracken Jr., professor of pediatrics.

Staishy Bostick Siem | EurekAlert!
Further information:
http://www.swmed.edu/

More articles from Health and Medicine:

nachricht Second cause of hidden hearing loss identified
20.02.2017 | Michigan Medicine - University of Michigan

nachricht Prospect for more effective treatment of nerve pain
20.02.2017 | Universität Zürich

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Breakthrough with a chain of gold atoms

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

Im Focus: DNA repair: a new letter in the cell alphabet

Results reveal how discoveries may be hidden in scientific “blind spots”

Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...

Im Focus: Dresdner scientists print tomorrow’s world

The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.

The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...

Im Focus: Mimicking nature's cellular architectures via 3-D printing

Research offers new level of control over the structure of 3-D printed materials

Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...

Im Focus: Three Magnetic States for Each Hole

Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".

Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Booth and panel discussion – The Lindau Nobel Laureate Meetings at the AAAS 2017 Annual Meeting

13.02.2017 | Event News

Complex Loading versus Hidden Reserves

10.02.2017 | Event News

International Conference on Crystal Growth in Freiburg

09.02.2017 | Event News

 
Latest News

Impacts of mass coral die-off on Indian Ocean reefs revealed

21.02.2017 | Earth Sciences

Novel breast tomosynthesis technique reduces screening recall rate

21.02.2017 | Medical Engineering

Use your Voice – and Smart Homes will “LISTEN”

21.02.2017 | Trade Fair News

VideoLinks
B2B-VideoLinks
More VideoLinks >>>