Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Heart disease associated with oral health – studies of women and serological factors

20.02.2004


A new study from Karolinska Institutet in Sweden shows, for the first time, an association between coronary heart disease and oral health in women. Recent results have also shown that serological factors, might provide insight into the reported epidemiological association between periodontitis and cardiovascular disease.



Cardiovascular disease (CVD) is the leading cause of death in the Western industrialized world. Classic risk factors such as smoking, obesity and high blood lipids do not explain all clinical and epidemiological features of CVD. Chronic inflammation has been suggested as a possible “unknown” risk factor. However, the chronic inflammatory disease periodontitis, has only recently been found to be associated to CVD.

A new study from Karolinska Institutet shows, for the first time, an association between coronary heart disease (CHD) and oral health in women. A group of 187 female patients with CHD had fewer remaining teeth (P<0.001) and more pathological periodontal pockets (P=0.002) compared to a control group. Dentures were more frequent (27% vs. 6%) as was edentulousness (10.5% vs. 0%) in the CHD group compared to the controls.


In another recent study from Karolinska Institutet risk factors for CVD were found in plasma from patients with periodontitis. Plasma levels of markers for arteriosclerosis and indices of inflammation in 50 patients with severe periodontitis were compared with those in 46 healthy cases. Total cholesterol levels were similar in the two groups, whereas levels of high density lipoproteins (HDL) were lower (P=0.007) and levels of C-reactive protein (CRP) were higher in the patient group. This is important, as both HDL and CRP are accepted risk factors for arteriosclerosis. Plasma levels of bacterial antigen specific IgA anti-Hsp60 antibodies were also lower in the patient group (P=0.0001). These serological differences might provide insight into the reported epidemiological association between periodontitis and CVD.

A possible mechanism behind the reported association could be the release of bacteria, bacterial products or pro-inflammatory cytokines from the periodontal lesions into the blood stream.

Ulla Bredberg Rådén | alfa
Further information:
http://www.ki.se

More articles from Health and Medicine:

nachricht New 3-D imaging reveals how human cell nucleus organizes DNA and chromatin of its genome
28.07.2017 | University of California - San Diego

nachricht Malaria Already Endemic in the Mediterranean by the Roman Period
27.07.2017 | Universität Zürich

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Abrupt motion sharpens x-ray pulses

Spectrally narrow x-ray pulses may be “sharpened” by purely mechanical means. This sounds surprisingly, but a team of theoretical and experimental physicists developed and realized such a method. It is based on fast motions, precisely synchronized with the pulses, of a target interacting with the x-ray light. Thereby, photons are redistributed within the x-ray pulse to the desired spectral region.

A team of theoretical physicists from the MPI for Nuclear Physics (MPIK) in Heidelberg has developed a novel method to intensify the spectrally broad x-ray...

Im Focus: Physicists Design Ultrafocused Pulses

Physicists working with researcher Oriol Romero-Isart devised a new simple scheme to theoretically generate arbitrarily short and focused electromagnetic fields. This new tool could be used for precise sensing and in microscopy.

Microwaves, heat radiation, light and X-radiation are examples for electromagnetic waves. Many applications require to focus the electromagnetic fields to...

Im Focus: Carbon Nanotubes Turn Electrical Current into Light-emitting Quasi-particles

Strong light-matter coupling in these semiconducting tubes may hold the key to electrically pumped lasers

Light-matter quasi-particles can be generated electrically in semiconducting carbon nanotubes. Material scientists and physicists from Heidelberg University...

Im Focus: Flexible proximity sensor creates smart surfaces

Fraunhofer IPA has developed a proximity sensor made from silicone and carbon nanotubes (CNT) which detects objects and determines their position. The materials and printing process used mean that the sensor is extremely flexible, economical and can be used for large surfaces. Industry and research partners can use and further develop this innovation straight away.

At first glance, the proximity sensor appears to be nothing special: a thin, elastic layer of silicone onto which black square surfaces are printed, but these...

Im Focus: 3-D scanning with water

3-D shape acquisition using water displacement as the shape sensor for the reconstruction of complex objects

A global team of computer scientists and engineers have developed an innovative technique that more completely reconstructs challenging 3D objects. An ancient...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Clash of Realities 2017: Registration now open. International Conference at TH Köln

26.07.2017 | Event News

Closing the Sustainability Circle: Protection of Food with Biobased Materials

21.07.2017 | Event News

»We are bringing Additive Manufacturing to SMEs«

19.07.2017 | Event News

 
Latest News

New 3-D imaging reveals how human cell nucleus organizes DNA and chromatin of its genome

28.07.2017 | Health and Medicine

Heavy metals in water meet their match

28.07.2017 | Power and Electrical Engineering

Oestrogen regulates pathological changes of bones via bone lining cells

28.07.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>