Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Diabetes doubles risk of liver disease and liver cancer

13.02.2004


In the largest study of its kind, researchers have shown that diabetes can cause chronic liver disease and cancer of the liver. Researchers from the Department of Veterans Affairs (VA) and the National Institutes of Health report their findings in the February issue of Gastroenterology, the journal of the American Gastroenterological Association.



The prospective cohort study was comprised of 173,643 patients with diabetes and 650,620 patients without diabetes who were discharged from VA hospitals between 1985 and 1990. These patients were tracked through 2000. Most were men (98 percent). The majority (99.5 percent) of diabetic patients had type II diabetes mellitus. Among diabetic patients, the incidence of chronic liver disease and cancer of the liver was about twice the incidence that of patients without diabetes.

A link between diabetes and liver disease was previously known; it was unknown whether diabetes caused liver disease or vice versa. Liver disease associated with diabetes is usually insidious, asymptomatic and goes undetected until a severe condition, such as liver cancer, occurs.


"Because of the significantly increased risk of developing liver disease, we recommend regular testing of liver enzymes for patients with diabetes," said study author Hashem El-Serag, MD, MPH, from the Houston VA Medical Center. "For patients with diabetes who receive oral medications, there has been a concern about toxicity in the liver – more reason to test liver enzymes early on and then periodically thereafter."

The risk for developing liver disease and liver cancer is highest among patients with long-standing (10+ years since diagnosis) diabetes. The increased risk is independent of alcoholic liver disease, viral hepatitis and demographic features. The public health significance of these findings is potentially large as it is estimated that 18.2 million people in the United States have diabetes.


Gastroenterology is the official journal of the American Gastroenterological Association, the oldest non-profit specialty medical society in the United States, with a membership of more than 13,000 physicians and researchers. Gastroenterology is the most prominent journal in the subspecialty and is in the top one percent of indexed medical journals internationally. Gastroenterology is published monthly.

Jessica Willocks | EurekAlert!
Further information:
http://www.gastro.org/

More articles from Health and Medicine:

nachricht A better way to measure the stiffness of cancer cells
01.03.2017 | Duke University

nachricht Humans have three times more brown body fat
01.03.2017 | Technische Universität München

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Researchers Imitate Molecular Crowding in Cells

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...

Im Focus: Safe glide at total engine failure with ELA-inside

On January 15, 2009, Chesley B. Sullenberger was celebrated world-wide: after the two engines had failed due to bird strike, he and his flight crew succeeded after a glide flight with an Airbus A320 in ditching on the Hudson River. All 155 people on board were saved.

On January 15, 2009, Chesley B. Sullenberger was celebrated world-wide: after the two engines had failed due to bird strike, he and his flight crew succeeded...

Im Focus: Breakthrough with a chain of gold atoms

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

Im Focus: DNA repair: a new letter in the cell alphabet

Results reveal how discoveries may be hidden in scientific “blind spots”

Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...

Im Focus: Dresdner scientists print tomorrow’s world

The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.

The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Booth and panel discussion – The Lindau Nobel Laureate Meetings at the AAAS 2017 Annual Meeting

13.02.2017 | Event News

Complex Loading versus Hidden Reserves

10.02.2017 | Event News

International Conference on Crystal Growth in Freiburg

09.02.2017 | Event News

 
Latest News

A better way to measure the stiffness of cancer cells

01.03.2017 | Health and Medicine

Exploring the mysteries of supercooled water

01.03.2017 | Physics and Astronomy

Research team of the HAW Hamburg reanimated ancestral microbe from the depth of the earth

01.03.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>