Killing the disease without killing the patient is an old dilemma for doctors fighting cancer and some of the tougher microorganisms such as fungal infections in individuals with suppressed immune systems. Drugs have little effect when a patients own immune system isnt available to help, and these fungi can resist external radiation that would kill even a perfectly healthy human. But they can be easily killed by a very small dose of radiation inside their cells.
Monoclonal antibodies can be designed to deliver radiation to specific cell types while sparing surrounding tissue. These designer antibodies, armed with radioactive isotopes, have been found to be highly effective against some types of cancer, but the combination may also be useful in other types of serious disease. This technique is known as radioimmunotherapy (RIT).
A study appearing in the February issue of The Journal of Nuclear Medicine demonstrates that radioimmunotherapy (RIT) provides a new, highly effective way to kill Cryptococcus neoformans and Histoplasma capsulatum, the fungi responsible for fungal meningitis and pneumonia, using much smaller levels of radiation than required to kill the fungi by external radiation. The study used organism-specific monoclonal antibodies coupled with radioactive isotopes of bismuth or rhenium.
Gavin McDonald | EurekAlert!
3D images of cancer cells in the body: Medical physicists from Halle present new method
16.05.2018 | Martin-Luther-Universität Halle-Wittenberg
Better equipped in the fight against lung cancer
16.05.2018 | Friedrich-Alexander-Universität Erlangen-Nürnberg
A research team led by physicists at the Technical University of Munich (TUM) has developed molecular nanoswitches that can be toggled between two structurally different states using an applied voltage. They can serve as the basis for a pioneering class of devices that could replace silicon-based components with organic molecules.
The development of new electronic technologies drives the incessant reduction of functional component sizes. In the context of an international collaborative...
At the LASYS 2018, from June 5th to 7th, the Laser Zentrum Hannover e.V. (LZH) will be showcasing processes for the laser material processing of tomorrow in hall 4 at stand 4E75. With blown bomb shells the LZH will present first results of a research project on civil security.
At this year's LASYS, the LZH will exhibit light-based processes such as cutting, welding, ablation and structuring as well as additive manufacturing for...
There are videos on the internet that can make one marvel at technology. For example, a smartphone is casually bent around the arm or a thin-film display is rolled in all directions and with almost every diameter. From the user's point of view, this looks fantastic. From a professional point of view, however, the question arises: Is that already possible?
At Display Week 2018, scientists from the Fraunhofer Institute for Applied Polymer Research IAP will be demonstrating today’s technological possibilities and...
So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics
Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...
The historic first detection of gravitational waves from colliding black holes far outside our galaxy opened a new window to understanding the universe. A...
02.05.2018 | Event News
13.04.2018 | Event News
12.04.2018 | Event News
24.05.2018 | Power and Electrical Engineering
23.05.2018 | Life Sciences
23.05.2018 | Life Sciences