Bone marrow stromal cells release a blood vessel-dilating hormone found in the brain -- a finding that suggests the hormone may be tapped to help with recovery from stroke or other neurological injuries disrupting blood flow to the central nervous system, researchers at the University of South Florida and James A. Haley Veterans Hospital report for the first time. The hormone is known as brain natriuretic peptide.
The laboratory study was published in the January 2004 issue of the journal Experimental Neurology.
"Were suggesting that transplanted bone marrow stromal cells may hasten recovery by releasing brain natriuretic peptide and other factors that improve blood flow to the brain and decrease swelling and pressure around the site of injury," said lead investigator Juan Sanchez-Ramos, MD, PhD, professor of neurology and research director at the USF Center for Aging and Brain Repair. "By helping irrigate, or restore the blood circulation to the brain, brain natriuretic factor may reduce the extent of damage from stroke or spinal cord injuries."
Anne DeLotto Baier | EurekAlert!
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