Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Early fevers associated with lower allergy risk later in childhood

10.02.2004


Infants who experience fevers before their first birthday are less likely to develop allergies by ages six or seven, according to a new study funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH). The study, published today in the Journal of Allergy and Clinical Immunology, lends support to the well-known "hygiene hypothesis," which contends that early exposure to infections might protect children against allergic diseases in later years.



The prevalence of asthma and allergies has increased dramatically worldwide in recent years," says Anthony S. Fauci, M.D., director of NIAID. "This study provides evidence that diminished exposure to early immunological challenges could be one of the reasons for this trend."

"The hygiene hypothesis is widely recognized but largely unproven," says Kenneth Adams, Ph.D., who oversees asthma research funded by NIAID. "The findings of this study strengthen the hypothesis and, after more research, could lead to preventative therapies for asthma and allergies."


The authors of the study followed the medical records of 835 children from birth to age 1, documenting any fever-related episodes. Fever was defined as a rectal temperature of 101 degrees Fahrenheit or above. At age 6 to 7 years, more than half of the children were evaluated for their sensitivity to common allergens, such as dust mites, ragweed and cats.

Researchers found that, of the children who did not experience a fever during their first year, 50.0 percent showed allergic sensitivity. Of those who had one fever, 46.7 percent became allergy-prone. The children who suffered two or more fevers in their infancy had greater protection, with only 31.3 percent showing allergic sensitivity by ages 6 to 7.

In particular, fever-inducing infections involving the eyes, ears, nose or throat appeared to be associated with a lower risk of developing allergies, compared with similar infections that did not result in fevers.

"We didn’t expect fever to relate with such a consistent effect," says Christine C. Johnson, Ph.D, M.P.H., senior research epidemiologist of the Henry Ford Health System in Detroit, MI, and one of the co-authors of the study. "It also was interesting that the more fevers an infant had, the less likely it was that he or she would be sensitive to allergies."

Dr. Johnson says that more research is needed to establish if early fevers have a direct effect on allergic development in children. Additionally, she and the other authors are working to determine if early exposure to pets as well as high levels of bacteria could also lower allergy risk. "If we can uncover which environmental factors affect allergic development and why, it may be possible to immunize children against these conditions," she says.


###
This study also received support from the National Institute of Environmental Health Sciences, another NIH component.

NIAID is a component of the National Institutes of Health (NIH), an agency of the U.S. Department of Health and Human Services. NIAID supports basic and applied research to prevent, diagnose and treat infectious diseases such as HIV/AIDS and other sexually transmitted infections, influenza, tuberculosis, malaria and illness from potential agents of bioterrorism. NIAID also supports research on transplantation and immune-related illnesses, including autoimmune disorders, asthma and allergies.

Reference:

L Keoki Williams et al. The relationship between early fever and allergic sensitization at age 6 to 7 years. Journal of Allergy and Clinical Immunology 113(2): 291-296 (2004).

Press releases, fact sheets and other NIAID-related materials are available on the NIAID Web site at http://www.niaid.nih.gov.

Paul Williams | NIAID News
Further information:
http://www.niaid.nih.gov/newsroom/releases/earlyfevers.htm
http://www.niaid.nih.gov

More articles from Health and Medicine:

nachricht Speed data for the brain’s navigation system
06.12.2016 | Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)

nachricht Study suggests possible new target for treating and preventing Alzheimer's
02.12.2016 | Oregon Health & Science University

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Significantly more productivity in USP lasers

In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.

Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...

Im Focus: Shape matters when light meets atom

Mapping the interaction of a single atom with a single photon may inform design of quantum devices

Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...

Im Focus: Novel silicon etching technique crafts 3-D gradient refractive index micro-optics

A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.

Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...

Im Focus: Quantum Particles Form Droplets

In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.

“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...

Im Focus: MADMAX: Max Planck Institute for Physics takes up axion research

The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.

The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ICTM Conference 2017: Production technology for turbomachine manufacturing of the future

16.11.2016 | Event News

Innovation Day Laser Technology – Laser Additive Manufacturing

01.11.2016 | Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

 
Latest News

Robot on demand: Mobile machining of aircraft components with high precision

06.12.2016 | Power and Electrical Engineering

A new dead zone in the Indian Ocean could impact future marine nutrient balance

06.12.2016 | Earth Sciences

Significantly more productivity in USP lasers

06.12.2016 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>